Critical care management of traumatic brain injury -- Surgical management of traumatic brain injury -- Traumatic and penetrating head injuries -- Blast-induced neurotrauma -- Indications and techniques for cranial decompression after traumatic brain injury -- Craniofacial injuries -- Prognosis after traumatic brain injury -- Traumatic cerebrospinal fluid fistulas -- Rehabilitation of patients with traumatic brain injury -- Cerebral blood flow and metabolism and cerebral ischemia -- Acute medical management of ischemic/hemorrhagic stroke -- Intraoperative cerebral protection -- Circulatory arrest with deep hypothermia -- Transcranial doppler ultrasonography and neurosonology -- Neurovascular imaging -- Carotid occlusive disease: natural history and medical management -- Carotid endarterectomy -- Carotid artery angioplasty and stenting -- Blunt cerebrovascular injury -- Nonatherosclerotic carotid lesions -- Extracranial vertebral artery diseases -- Intracranial occlusive disease -- Adult moyamoya disease -- Cerebral venous and sinus thrombosis -- Nonlesional spontaneous intracerebral hemorrhage -- Genetics of intracranial aneurysms -- The natural history of cerebral aneurysms -- Surgical decision making for the treatment of intracranial aneurysms -- Pathobiology of intracranial aneurysms -- Surgical decision making for the treatment of intracranial aneurysms -- Perioperative management of subarachnoid hemorrhage -- Cerebral vasospasm -- Surgical approaches to intracranial aneurysms -- Microsurgery of paraclinoid aneurysms -- Intracranial internal carotid artery aneurysms -- Anterior communicating artery aneurysms -- Microsurgery of distal anterior cerebral artery aneurysms -- Surgical management of middle cerebral artery aneurysms -- Microsurgery of vertebral artery, posterior inferior cerebellar artery, and vertebrobasilar junction aneurysms -- Basilar trunk aneurysms -- Microsurgery of basilar apex aneurysms -- Endovascular approaches to intracranial aneurysms -- Endovascular coiling of intracranial aneurysms: supporting evidence -- Endovascular stenting of intracranial aneurysms -- Endovascular hunterian ligation -- Microsurgical management of giant intracranial aneurysms -- Infectious intracranial aneurysms -- Revascularization techniques for complex aneurysms and skull base tumors -- Multimodality management of complex cerebrovascular lesions -- Traumatic cerebral aneurysms secondary to penetrating intracranial injuries -- Pathobiology of true arteriovenous malformations -- The natural history of intracranial vascular malformations -- Therapeutic decision making -- Adjuvant endovascular management of brain arteriovenous malformations -- Endovascular management of arteriovenous malformations for cure -- Microsurgical management of arteriovenous malformations -- Surgical and radiosurgical management of giant arteriovenous malformations -- Carotid-cavernous fistulas -- Treatment of other intracranial dural arteriovenous fistulas -- Natural history of cavernous malformations -- Genetics of cerebral cavernous malformations -- Supratentorial and infratentorial cavernous malformations -- Classification of spinal arteriovenous lesions: arteriovenous fistulas and arteriovenous malformations -- Endovascular treatment of spinal vascular malformations -- Spinal vascular malformations -- Pregnancy and the vascular lesion
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Current status and future direction of management of spinal cord injury -- Intraoperative monitoring of the spinal cord and nerve roots -- Concepts of disk degeneration and regeneration -- Bone metabolism and osteoporosis and its effects on spinal disease and surgical treatments -- Differential diagnosis and initial management of spine pathology -- Diagnosis and management of diskogenic lower back pain -- Metabolic and other nondegenerative causes of low back pain -- Evaluation, indications, and techniques of revision spine surgery -- Infections of the spine -- Fungal and tubercular infections of the spine -- Treatment of disk and ligamentous diseases of the cervical spine -- Posterior approach to cervical degenerative disease -- Anterior approach for cervical spondylotic myelopathy -- Spondyloarthropathies (including ankylosing spondylitis) -- Ossification of the posterior longitudinal ligament and other enthesopathies -- Treatment of thoracic disk herniation -- Treatment of disk disease of the lumbar spine -- Lumbar spine stenosis -- Pediatric spondylolisthesis -- Adult thoracolumbar scoliosis -- Flat back and sagittal plane deformity -- Acquired abnormalities of the craniocervical junction -- Congenital abnormalities of the thoracic and lumbar spine -- Basic principles of spinal internal fixation -- Bone graft options, bone graft substitutes, and bone harvest techniques -- Cervical arthroplasty -- Lumbar arthroplasty: total disk replacement and nucleus replacement technologies -- Nucleoplasty and posterior dynamic stabilization systems -- Spinopelvic fixation -- Anterior cervical instrumentation -- Occiput, C1, and C2 instrumentation -- Posterior subaxial and cervicothoracic instrumentation -- Anterior thoracic instrumentation -- Posterior thoracic instrumentation -- Anterior lumbar instrumentation -- Posterior lumbar instrumentation -- Posterior, transforaminal, and anterior lumbar interbody fusion: techniques and instrumentation -- Image-guided spinal navigation: principles and clinical applications -- Thoracoscopic approaches to the spine -- Minimally invasive techniques for lumbar disorders -- Tumors of the craniovertebral junction -- Spinal cord tumors in adults -- Evaluation and management of spinal axis tumors: benign and primary malignant -- Evaluation and management of spinal axis tumors: metastatic -- Assessment of the cervical spine after trauma -- Evaluation and management of craniocervical dissociation -- Atlantoaxial rotatory subluxation, transverse ligament injury -- Evaluation and treatment of odontoid and hangman's fractures -- Pathology of the cervicothoracic junction: evaluation and treatment -- Transient quadriparesis and athletic injuries of the cervical spine -- Diagnosis and management of thoracic spine fractures -- Thoracolumbar trauma -- Sacral fractures -- Osteoporotic fractures: evaluation and treatment with vertebroplasty and kyphoplasty -- V. 4: -- Introduction to traumatic brain injury -- Epidemiology of traumatic brain injury -- Biomechanical basis of traumatic brain injury -- Neuropathology of traumatic brain injury -- Animal models of traumatic brain injury -- Neurochemical pathomechanisms in traumatic brain injury -- Regeneration and repair -- Current concepts of hypothermia in traumatic brain injury -- Imaging of traumatic brain injury -- Clinical pathophysiology of traumatic brain injury -- Mild traumatic brain injury in adults and concussion in sports -- Initial resuscitation, prehospital care, and emergency room care in traumatic brain injury --
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Intracranial ependymomas in adults -- Hemangioblastomas -- Central nervous system lymphoma -- Metastatic brain tumors -- Meningiomas -- Meningeal sarcoma and meningeal hemangiopericytoma -- Acoustic neuroma -- Pituitary tumors: functioning and nonfunctioning -- Craniopharyngioma -- Epidermoid, dermoid, and neurenteric cysts -- Neoplastic meningitis -- Ventricular tumors -- Overview of skull base tumors -- Chordomas and chondrosarcomas -- Glomus tumors -- Neoplasms of the paranasal sinuses -- Esthesioneuroblastoma -- Trigeminal schwannomas -- Juvenile nasal angiofibroma -- Osseous tumors -- Tumors of the orbit -- Skull tumors -- Scalp tumors -- Pseudotumor cerebri -- Sarcoidosis, tuberculosis, and xanthogranuloma -- Demyelinating disease -- Pain: general historical considerations -- Anatomy and physiology of pain -- Molecular basis of nociception -- Approach to the patient with chronic pain -- Pharmacologic treatment of pain -- Management of pain by anesthetic techniques -- Evidence-based approach to the treatment of facial pain -- Trigeminal neuralgia: diagnosis and nonoperative management -- Percutaneous procedures for trigeminal neuralgia -- Stereotactic radiosurgery for trigeminal neuralgia -- Microvascular decompression for trigeminal neuralgia -- Neurosurgical management of intractable pain -- Evidence base: neurostimulation for pain -- Peripheral nerve stimulation for neuropathic pain -- Spinal cord stimulation -- Motor cortex stimulation -- Evidence base for destructive procedures -- Diagnosis and management of painful neuromas -- Dorsal root entry zone lesions -- Percutaneous cordotomy and trigeminal tractotomy-nucleotomy -- Neuroanesthesia in children -- Neurocritical care in children -- Normal and abnormal embryology of the brain -- Encephalocele -- Dandy-Walker syndrome -- Arachnoid cysts -- Chiari malformations -- Craniopagus twins -- Genetics of craniosynostosis -- Craniosynostosis -- Syndromic craniosynostosis -- Endoscopic treatment of craniosynostosis -- Plagiocephaly -- Hydrocephalus in children: approach to the patient -- Infantile posthemorrhagic hydrocephalus -- Cerebrospinal fluid physiology -- Experimental hydrocephalus -- Ventricular shunting procedures -- Neuroendoscopy -- Cerebrospinal fluid devices -- Shunt infections and their treatment -- General approaches and considerations for pediatric brain tumors -- Optic pathway hypothalamic gliomas -- Thalamic tumors -- Choroid plexus tumors -- Pediatric craniopharyngioma -- Supratentorial hemispheric tumors -- Ependymoma -- Medulloblastoma in children -- Cerebellar astrocytomas -- Brainstem glioma -- Intracranial germ cell tumors -- Familial tumors (neurocutaneous syndromes) -- Skull tumors and fibrous dysplasia -- Moyamoya disease -- Vein of galen aneurysmal malformation -- Management of severe head injury in children -- Child abuse -- Growing skull fracture -- Birth head trauma -- Birth brachial plexus injury --
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Myelomeningocele and myelocystocele -- Lipomyelomeningocele -- Split spinal cord -- Tethered spinal cord: fatty filum terminale, meningocele manqué, and dermal sinus tracts -- Developmental abnormalities of the craniocervical junction -- Achondroplasia and other dwarfisms -- Cervical spine disorders in children -- Intramedullary spinal cord tumors in children -- Spine tumors in children -- Thoracolumbar spinal disorders in pediatric patients -- Vertebral column and spinal cord injuries in children -- Clinical features and management of cerebral palsy -- Intrathecal baclofen therapy for cerebral palsy -- Selective dorsal rhizotomy for spastic cerebral palsy -- Dystonia in children -- V. 3: -- General principles in evaluating and treating peripheral nerve pathology, injuries, and entrapments and their historical context -- Pathophysiology of surgical nerve disorders -- Peripheral nerve examination, evaluation, and biopsy -- Electrodiagnostic evaluation of peripheral nerves: electromyography and nerve conduction studies -- Peripheral neuropathies -- Operative neurophysiology of peripheral nerves -- Imaging for peripheral nerve disorders -- Distal entrapment syndromes: carpal tunnel, cubital tunnel, peroneal, and tarsal tunnel -- Thoracic outlet syndrome -- Piriformis syndrome, obturator internus syndrome, pudendal nerve entrapment, and other pelvic entrapments -- Techniques and options in nerve reconstruction and repair -- Management of acute peripheral nerve injuries -- Early management of brachial plexus injuries -- Secondary procedures for brachial plexus injuries -- Nerve injuries of the lower extremity -- Benign tumors of the peripheral nerve -- Surgery for malignant peripheral nerve sheath tumors -- Pain, complications, and iatrogenic injury in nerve surgery -- General and historical considerations of radiotherapy and radiosurgery -- Principles of radiation therapy -- The radiobiology and physics of radiosurgery -- Fractionated radiation therapy for malignant brain tumors -- Fractionated radiation therapy for benign brain tumors -- Fractionated radiotherapy for spine tumors -- Interstitial and intracavitary irradiation of brain tumors -- Proton radiosurgery -- Linear accelerator radiosurgery: technical aspects -- Gamma knife radiosurgery -- Image-guided robotic radiosurgery: the CyberKnife -- Radiosurgery of malignant tumors -- Radiosurgery of benign intracranial tumors -- Radiosurgery for intracranial vascular malformations -- Radiosurgery for functional disorders -- Stereotactic radiosurgery for the treatment of spinal metastases -- Radiosurgery for benign spine tumors and vascular malformations -- Overview and historical considerations -- Concepts and mechanisms of spinal biomechanics -- Biomaterials and biomechanics of spinal arthroplasty -- Principles of translation of biologic therapies in spinal cord injury --
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Topectomy and multiple subpial transection -- Hemispheric dissconnection procedures -- Vagus nerve stimulation for intractable epilepsy -- Radiosurgical treatment of epilepsy -- Deep brain stimulation for epilepsy -- Epilepsy surgery: outcome and complications -- Introduction -- Anatomy and synaptic connectivity of the basal ganglia -- Rationale for surgical interventions in movement disorders -- Neuropathology of movement disorders -- Clinical overview of movement disorders -- Patient selection criteria for deep brain stimulation in movement disorders -- Functional imaging in movement disorders -- Surgical management of tremor -- Pallidal interventions for Parkinson's disease -- Subthalamic deep brain stimulation for Parkinson's disease -- Subthalamotomy in Parkinson's disease: indications and outcome -- Deep brain stimulation for dystonia -- Deep brain stimulation: mechanisms of action -- Emerging and experimental neurosurgical treatments for parkinson's disease -- Seletive peripheral denervation for cervical dystonia -- A history of psychosurgery -- Surgery for Tourette's syndrome -- Surgery for obsessive-compulsive disorder -- Surgical treatment of major depression -- Ablative surgery for spasticity -- Management of spasticity by central nervous system infusion techniques -- Treatment of intractable vertigo -- Treatment applications of cortical stimulation -- Neuroprosthestics -- V. 2: -- Brain tumors: general considerations -- Brain tumors: an overview of current histopathologic classifications -- Brain tumor immunology and immunotherapy -- Brain tumor stem cells -- Proliferation markers in the evaluation of gliomas -- Molecular genetics and the development of targets for glioma therapy -- Growth factors in glial tumors -- The genetic origins of brain tumors -- Invasion in malignant glioma -- Angiogenesis and brain tumors: molecular targets and molecular scalpels -- Barriers to delivery of therapeutics to brain tumors -- Epidemiology of brain tumors -- Gene- and viral-based therapies for gliomas -- Clinical features: neurology of brain tumor and paraneoplastic disorders -- Radiologic features of central nervous system tumors -- Endovascular techniques for tumor embolization -- Brain tumors during pregnancy -- Principles of chemotherapy -- Brain tumor outcome studies: design and interpretation -- Frame and frameless stereotactic brain biopsy -- Basic principles of cranial surgery for brain tumors -- Basic principles of skull base surgery -- Surgical complications of brain tumors and their avoidance -- Navigation for brain tumors -- Endoscopic approaches to brain tumors -- Intraoperative magnetic resonance imaging -- Low-grade gliomas: astrocytoma, oligodendroglioma, and mixed glioma -- Malignant gliomas: anaplastic astrocytoma, glioblastoma multiforme, gliosarcoma -- Unusual gliomas -- Primitive neuroectodermal tumors -- Pineal tumors -- Medulloblastoma --
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V. 1: -- Historical overview of neurosurgery -- Surgical anatomy of the brain -- Molecular biology primer for neurosurgeons -- Neuroembryology -- Stem cell biology in the central nervous system -- Neurons and neuroglia -- Cellular mechanisms of brain energy metabolism -- Blood-brain barrier -- Cerebral edema -- Physiology of the cerebrospinal fluid and intracranial pressure -- Neurosurgical epidemiology and outcomes assessment -- Altered consciousness -- Neuroophthalmology -- Neurotology -- Neurourology -- Neuropsychological testing -- Computed tomography and magnetic resonance imaging of the brain -- Radiology of the spine -- Physiologic evaluation of the brain with magnetic resonance imaging -- Molecular imaging of the brain with positron emission tomography -- Neuroanesthesia: preoperative evaluation -- Avoidance of complications in neurosurgery -- Intracranial pressure monitoring -- Principles of neurocritical care -- Surgical planning: overview -- Positioning for cranial surgery -- Patient positioning for spinal surgery -- Positioning in peripheral nerve surgery -- Incisions and closures -- Advantages and limitations of cranial endoscopy -- Thorascopic spine surgery -- Cranioplasty -- Production and flow of cerebrospinal fluid -- Clinical evaluation of adult hydrocephalus -- Shunting -- Adult hydrocephalus: the role of endoscopic third ventriculostomy -- Pathophysiology of subdural hematomas -- Medical and surgical management of chronic subdural hematomas -- Basic science of central nervous system infections -- Postoperative infections of the head and brain -- Postoperative infections of the spine -- The use and misuse of antibiotics in neurosurgery -- Brain abscess -- Meningitis and encephalitis -- Acquired immune deficiency syndrome -- Parasitic infections -- Surgical risk of transmittable diseases -- Epilepsy surgery overview -- Electrophysiologic properties of the mammalian central nervous system -- Animal models of epilepsy -- Malformations of cortical development -- Diagnosis and classification of seizures and epilepsy -- Antiepileptic medications: principles of clinical use -- Continuous electroencephalography in neurological-neurosurgical intensive care: applications and value -- Neuroradiologic evaluation for epilepsy surgery -- Evaluation of patients for epilepsy surgery -- Motor, sensory, and language mapping and monitoring for cortical resections -- Auditory language mapping -- Investigation of human cognition in epilepsy surgery patients -- Intracranial monitoring -- Surgery for extratemporal lobe epilepsy -- Standard temporal lobectomy -- Selective amygdalohippocampectomy -- Tailored resections for epilepsy --