edited by Paolo Fortina (Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia, PA, USA), Eric Londin (Department of Pathology, Anatomy and Cell Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA), Jason Y. Park (Department of Pathology, UT Southwestern Medical Center and Children's Medical Center, Dallas, TX, US), Larry J. Kricka (Department of Pathology, and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, USA).
.PUBLICATION, DISTRIBUTION, ETC
Place of Publication, Distribution, etc.
New York, NY :
Name of Publisher, Distributor, etc.
Humana Press,
Date of Publication, Distribution, etc.
[2017]
PHYSICAL DESCRIPTION
Specific Material Designation and Extent of Item
xi, 278 pages :
Other Physical Details
illustrations ;
Dimensions
27 cm.
SERIES
Series Title
Methods in molecular biology,
Series Title
Springer protocols
Volume Designation
1633
ISSN of Series
1064-3745 ;
INTERNAL BIBLIOGRAPHIES/INDEXES NOTE
Text of Note
Includes bibliographical references and index.
SUMMARY OR ABSTRACT
Text of Note
This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival. The chapters in this book cover topics such as: cytochemical staining, single-cell mass cytometry of AML and Leukemia stem/progenitor cells, microsphere-based assessment of DNA methylation for AML prognosis, a zebrafish model for evaluating the function of human leukemic gene IDH1 and its mutation, and the isolation of biologically active exosomes from plasma of patients with cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Acute Myeloid Leukemia: Methods and Protocols is a valuable resource for scientists and researchers to further their studies and advancements in the field of AML.