Antioxidant Properties and Anti-Cancer Effects of Polyphenols in Sweetpotato Leaves
نام عام مواد
[Thesis]
نام نخستين پديدآور
Bolanos, Josue
نام ساير پديدآوران
Lee, Sun-Ok
وضعیت نشر و پخش و غیره
نام ناشر، پخش کننده و غيره
University of Arkansas
تاریخ نشرو بخش و غیره
2020
مشخصات ظاهری
نام خاص و کميت اثر
66
یادداشتهای مربوط به پایان نامه ها
جزئيات پايان نامه و نوع درجه آن
M.S.
کسي که مدرک را اعطا کرده
University of Arkansas
امتياز متن
2020
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
Although the root is widely consumed, sweetpotato leaves (SPL) are often discarded and are only consumed in a few countries. In the United States, SPL consumption is limited to private gardens, particularly in the Southeastern United States. Not only are SPL a good source of nutrients such as vitamins and minerals, but they also contain polyphenol compounds including the caffeoylquinic acid derivatives and carotenoids such as lutein. Several studies have shown the polyphenol contents and antioxidant capacities of SPL, which vary based on year and variety, while few studies have shown anti-colon cancer effects of SPL. Therefore, this study investigated the impact of year and variety on the antioxidant capacity and total polyphenol content of SPL and the in vitro anti-colon cancer effects of SPL on cell viability and apoptosis in Caco-2 cells. The results showed that the 2019 SPL possessed higher total polyphenols and antioxidant capacity compared to the 2018 SPL. Among 2019 SPL varieties, SPL1, SPL3, SPL9, SPL11, and SPL28 were selected to evaluate further anti-colon effects. In these 5 SPL varieties with the highest antioxidant and polyphenol amounts, the major polyphenols, 3,5-dicaffeoylquinic acid, 3,4-dicaffeoylquinic acid, and chlorogenic acid, were identified and quantified. All 5 samples significantly decreased cell viability in a dose-dependent manner and significantly increased apoptosis at 600 µg/mL (p < 0.05). Polyphenols and carotenoids are known to be bioactive compounds with potential health-promoting properties. The findings of the present study support that SPLs contain anti-colon cancer properties, and further research is needed.
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Chemistry
موضوع مستند نشده
Food science
موضوع مستند نشده
Nutrition
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )