عنوان

Membrane transporters :

شابک

1280842636

شابک

1588291049

شابک

1592593879

شابک

6610842639

شابک

9781280842634

شابک

9781588291042

شابک

9781592593873

شابک

9786610842636

شماره

b744478

عنوان اصلي

Membrane transporters :

نام عام مواد

[Book]

ساير اطلاعات عنواني

methods and protocols /

نام نخستين پديدآور

edited by Qing Yan.

محل نشرو پخش و غیره

Totowa, NJ :

نام ناشر، پخش کننده و غيره

Humana Press,

تاریخ نشرو بخش و غیره

2003.

نام خاص و کميت اثر

1 online resource (xii, 369 pages) :

ساير جزييات

illustrations

عنوان فروست

Methods in molecular biology ;

مشخصه جلد

227

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

Pharmacogenomics of membrane transporters an overview / Q. Yan -- The iubmb-endorsed transporter classification system / W. Busch and M.H. Saier, Jr. -- Bioinformatics and data integration in membrane transporter studies / Q. Yan -- DNA microarrays to analyze gene expression in animals with altered transporter expression / G.W. Miller -- Microarray data analysis in studies of membrane transporters / D. Hu -- Laser capture microdissection to examine transporter expression in specific cell regions / O. Rho and G.W. Miller -- Site-directed mutagenesis in the study of membrane transporters / R.M. Ryan, A.D. Mitrovic and R.J. Vandenberg -- Fluorescence techniques for studying membrane transport proteins: The p-glycoprotein multidrug transporter / F.J. Sharom [and others] -- Reconstitution of membrane transporters / F.J. Sharom and P.D. Eckford -- Equilibrium binding and transport studies / A.M. Ojeda [and others] -- Electrophysiological studies of ion channels and therapeutic potential with adenovirus-mediated gene transfer / J. Qu, T.V. Pham and M.N. Obreztchikova -- Antibody production and immunocytochemical localization of amino acid transporters / D.V. Pow, R. Sullivan and H. Scott -- Xenopus laevis oocytes / S. Broer -- Measurement of intracellular ph / F.B. Loiselle and J.R. Casey -- Small-angle x-ray scattering studies of membrane transporter peripheral components and soluble domains / B.H. Shilton -- Membrane protein nmr studies / S.J. Opella -- Analysis of soluble sugar permease domains by solution nmr / T.A. Wilkinson and Y. Chen -- Molecular modeling and molecular dynamics simulations of membrane transporter proteins / D.S. Dwyer -- Imaging plasma membrane proteins by confocal microscopy / S.W. Tsang and P.M. Haney.

بدون عنوان

0

متن يادداشت

Membrane transporters and channels play key roles in drug absorption and distribution, influence drug efficacy and toxicity, and are the target of about 30% of currently marketed drugs. In Membrane Transporters: Methods and Protocols, a panel of recognized basic and clinical investigators-many world-famous-describe their proven, cutting-edge methodologies for studying these important proteins. Treated in step-by-step detail, these techniques take advantage of all the latest developments in biomedical research, including pharmacogenomics, bioinformatics, and microarray technologies. The authors explain databases and tools for bioinformatics analysis, provide practical guidelines for microarray experiments and data analysis, and illustrate the use of small-angle X-ray scattering, nuclear magnetic resonance (NMR), and molecular modeling to study the structural biology of membrane transporters. Methods for exploring structure-function correlation, such as site-directed mutagenesis, immunocytochemistry, and confocal microscopy, are also described, along with several methods that may help in the development of novel therapeutics. Each technique contains hands-on instructions, many notes on avoiding the problems that one may encounter, and suggestions for variant procedures. Comprehensive and highly practical, Membrane Transporters: Methods and Protocols offers investigators working in biopharmaceutical science, drug discovery, and drug delivery both an array of powerful tools for work on membrane transporters and an essential guide to the state-of-the-art in the membrane transporter field today.

عنوان

Membrane transporters.

شماره استاندارد بين المللي کتاب و موسيقي

9781588291042

موضوع مستند نشده

Biological transport, Active, Laboratory manuals.

موضوع مستند نشده

Carrier proteins, Laboratory manuals.

موضوع مستند نشده

Ion channels, Laboratory manuals.

موضوع مستند نشده

Membrane proteins, Laboratory manuals.

موضوع مستند نشده

Membrane Transport Proteins.

موضوع مستند نشده

Pharmacogenetics.

موضوع مستند نشده

Biological transport, Active.

موضوع مستند نشده

Biologisch transport.

موضوع مستند نشده

Carrier proteins.

موضوع مستند نشده

Ion channels.

موضوع مستند نشده

Membrane proteins.

موضوع مستند نشده

Membranen.

موضوع مستند نشده

SCIENCE-- Life Sciences-- Cell Biology.

موضوع مستند نشده

Wetenschappelijke technieken.

موضوع مستند نشده

PSF.

موضوع مستند نشده

SCI-- 017000

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

شماره رده

نشانه اثر

نشانه اثر

مستند نام اشخاص تاييد نشده

Yan, Qing,1971-

تاريخ عمليات

20201204045235.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y