عنوان

Antiviral RNAi :

شابک

1617790370

شابک

9781617790379

شابک اشتباه

1617790362

شابک اشتباه

9781617790362

شماره

b730610

عنوان اصلي

Antiviral RNAi :

نام عام مواد

[Book]

ساير اطلاعات عنواني

concepts, methods, and applications /

نام نخستين پديدآور

edited by Ronald P. van Rij.

محل نشرو پخش و غیره

New York, N.Y. :

نام ناشر، پخش کننده و غيره

Humana Press,

تاریخ نشرو بخش و غیره

©2011.

نام خاص و کميت اثر

1 online resource (xi, 411 pages) :

ساير جزييات

illustrations (some color)

عنوان فروست

Methods in molecular biology,

عنوان فروست

Springer protocols

مشخصه جلد

721

شاپا ي ISSN فروست

1940-6029 ;

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

Viruses and RNAi share an intricate relationship at many levels. RNAi is an important antiviral defense mechanism in plants and invertebrates, microRNAs - of viral or cellular origin - affect many aspects of virus biology, and replication of many, if not all, mammalian viruses can be suppressed by RNAi. Antiviral RNAi: Concepts, Methods, and Applications provides a collection of protocols for the analysis of viral small RNAs and natural antiviral RNAi responses as well as for the development and optimization of RNAi-based antiviral drugs. As RNAi is a central regulatory mechanism in the cell, the methods in this volume can also be applied out of the context of a virus infection. Divided into five convenient parts, this detailed volume reviews important basic concepts in the field of antiviral RNAi, provides experimental and bio-informatic tools for the analysis of small silencing RNAs, covers methods to biochemically dissect RNAi-based antiviral defense and viral counter-defense mechanisms, describes methods for the design, expression, and delivery of therapeutic antiviral siRNAs, and finally presents genome-wide RNAi approaches for the identification of factors involved in virus replication. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Antiviral RNAi: Concepts, Methods, and Applications serves as an ideal guide for both novice and experienced researchers alike striving to dissect the role of RNAi in the viral life cycle or to further boost the development of novel therapeutics and experimental tools based on RNAi technology.

منبع سفارش / آدرس اشتراک

Springer

شماره انبار

978-1-61779-036-2

عنوان

Antiviral RNAi.

شماره استاندارد بين المللي کتاب و موسيقي

9781617790362

موضوع مستند نشده

Antiviral agents.

موضوع مستند نشده

Gene silencing.

موضوع مستند نشده

RNA.

موضوع مستند نشده

Antiviral Agents.

موضوع مستند نشده

Genetic Therapy.

موضوع مستند نشده

MicroRNAs.

موضوع مستند نشده

RNA Interference.

موضوع مستند نشده

RNA, Small Interfering.

موضوع مستند نشده

Virus Diseases-- therapy.

موضوع مستند نشده

Antiviral agents.

موضوع مستند نشده

Gene silencing.

موضوع مستند نشده

RNA.

موضوع مستند نشده

MED107000

موضوع مستند نشده

MFN

شماره

ويراست

شماره رده

شماره رده

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

Rij, Ronald P. van.

تاريخ عمليات

20201203133518.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y