عنوان

Antimicrobial peptides :

شابک

9789811335884

شابک

9789811335891

شابک

9811335885

شابک

9811335893

شابک اشتباه

9789811335877

شابک اشتباه

9811335877

عنوان اصلي

Antimicrobial peptides :

نام عام مواد

[Book]

ساير اطلاعات عنواني

basics for clinical application /

نام نخستين پديدآور

Katsumi Matsuzaki, editor.

محل نشرو پخش و غیره

Singapore :

نام ناشر، پخش کننده و غيره

Springer,

تاریخ نشرو بخش و غیره

2019.

نام خاص و کميت اثر

1 online resource (viii, 304 pages) :

ساير جزييات

illustrations (some color)

عنوان فروست

Advances in experimental medicine and biology,

مشخصه جلد

volume 1117

شاپا ي ISSN فروست

0065-2598 ;

متن يادداشت

Includes index.

متن يادداشت

Part 1. Introduction -- Chapter 1. Antimicrobial peptides of multicellular organisms: My perspective -- Part 2. Mechanisms of Antimicrobial Action -- Chapter 2. Membrane permeabilization mechanisms -- Chapter 3. Elementary processes and mechanisms of interactions of antimicrobial peptides with membranes -- single GUV studies -- Chapter 4. The mechanisms of action of cationic antimicrobial peptides refined by novel concepts from biophysical investigations -- Chapter 5. Anionic lipid clustering model -- Chapter 6. Intracellular antimicrobial peptides targeting the protein synthesis machinery -- Part 3. Other activities of AMPs -- Chapter 7. Antimicrobial and cell-penetrating peptides: How to understand two distinct functions despite similar physicochemical properties -- Chapter 8. Synthetic anti-lipopolysaccharide peptides (SALP) as effective inhibitors of pathogen-associated molecular patterns (PAMPs) -- Chapter 9. Anti-cancer activities of natural and synthetic peptides -- Chapter 10. Antimicrobial host defence peptides: Immunomodulatory functions and translational prospects -- Part 4. Towards Clinical Applications -- Chapter 11. Activity and selectivity of antimicrobial peptides: A complex interplay of multiple equilibria -- Chapter 12. Design of antimicrobial peptides: Progress made with human cathelicidin LL-37 -- Chapter 13. Application of synthetic molecular evolution to the discovery of antimicrobial peptides -- Chapter 14. AMPs as anti-biofilm agents for human therapy and prophylaxis -- Chapter 15. Clinical application of AMPs.

بدون عنوان

0

متن يادداشت

This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.

منبع سفارش / آدرس اشتراک

Springer Nature

شماره انبار

com.springer.onix.9789811335884

شماره استاندارد بين المللي کتاب و موسيقي

9789811335877

موضوع مستند نشده

Peptide antibiotics.

موضوع مستند نشده

MEDICAL-- Pharmacology.

موضوع مستند نشده

Peptide antibiotics.

موضوع مستند نشده

MED-- 071000

موضوع مستند نشده

MKG

موضوع مستند نشده

MMG

شماره

ويراست

شماره رده

مستند نام اشخاص تاييد نشده

Matsuzaki, Katsumi

تاريخ عمليات

20200823234228.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y