عنوان

Clinical Use of Antibodies :

شابک

9401135169

شابک

9789401135160

شماره

b595240

عنوان اصلي

Clinical Use of Antibodies :

نام عام مواد

[Book]

ساير اطلاعات عنواني

Tumours, infection, infarction, rejection and in the diagnosis of AIDS

نام نخستين پديدآور

edited by Richard P. Baum, Peter H. Cox, Gustav Hör, Gian Luigi Buraggi.

محل نشرو پخش و غیره

Dordrecht

نام ناشر، پخش کننده و غيره

Springer Netherlands

تاریخ نشرو بخش و غیره

1991

نام خاص و کميت اثر

(x, 185 pages)

عنوان فروست

Developments in nuclear medicine, 19.

متن يادداشت

1. Advances in cancer imaging and therapy with radiolabelled antibodies --; 2. Evaluation of the diagnostic utility of immunoscintigraphy in oncology --; 3. The quality control and clinical testing of radiolabelled antibodies --; 4. Clinical utility of radiolabelled monoclonal antibodies in the management of gastrointestinal cancer --; 5. Use of 123-I radiolabelled F(AB')2 fragments of anti-CEA monoclonal antibody for the detection of primary and metastatic gastrointestinal carcinomas --; 6. Bispecific monoclonal antibodies for two phase radioimmunotherapy --; 7. Antimyosin antibody imaging in myocardial infarction --; 8. Antimyosin based radioimmunodetection of myocarditis cardiomyopathy and cardiac transplant rejection --; 9. Recent advances in the use of radiolabelled monoclonal antibodies in the management of ovarian cancer --; 10. Monoclonal antibodies for cell labelling with particular reference to thrombus imaging --; 11. The role of nuclear medicine in the evaluation of the patient with acquired immune deficiency syndrome (AIDS) --; 12. Detection of inflammation/infection using radiolabelled anti-granulocyte antibodies: possibilities and limitations --; 13. A new marker for the detection of adenocardinomas by radioimmunoscintigraphy --; 14. New developments in the diagnosis of AIDS and strategies for therapy.

متن يادداشت

It was at Frankfurt/Mainin 1899 that Paul Ehrlich first expounded his famous "site-chain theory"--Which described the basic immunological principal of antibody-antigen interactio- on the occasion of the opening of the Institute for Experimental Therapeutics (which was later named after him). Nearly 100 years have passed since, and in retrospect it can be said that the "Ehrlich Era" (first steps in immunology "Magic Bullet" concept) and the "Behring Era" (detection of antibodies and serum therapy) formed the essential basis in the development of immunology. Niels K. Jerne, the former director of the Paul Ehrlich Institute in Frankfurt/Main received, together with Georges Kohler and Cesar Milstein, the Nobel Prize in Medicine 1984. These late successors of Ehrlich and Behring first described the hybridoma technology (in 1975) which enabled one of the most important and revolutionary technological innovations in the field of immunology -the production of monoclonal antibodies. It happens that, the time of the publication of this book, just a decade has passed since the first use of radiolabelled monoclonal antibodies in man (by the Lausanne Group). Over these 10 years a tremendous progress has taken place in the field of immunoscintigraphy:A large panel of highly specific monoclonal antibodies against tumour-associated antigens as well as normal cell compounds have been developed. Enormous progress has been made in the field of radiolabelling -from iodine-131 to technetium-99mor even positron-emittingradionuclides, e. g. iodine-124.

موضوع مستند نشده

Medical radiology.

موضوع مستند نشده

Medicine.

موضوع مستند نشده

Nuclear medicine.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

edited by Richard P. Baum, Peter H. Cox, Gustav Hör, Gian Luigi Buraggi.

مستند نام اشخاص تاييد نشده

Gian Luigi Buraggi

مستند نام اشخاص تاييد نشده

Gustav Hör

مستند نام اشخاص تاييد نشده

Peter H Cox

مستند نام اشخاص تاييد نشده

Richard P Baum

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y