۱۴۸۷۷پ
per
پراکندگی شیوع بیماری فنیل کتونوری در جهان و ایران :مرورسیستماتیک و متاآنالیز
/پرستو مرادی
: جغرافیا و برنامه ریزی
، ۱۳۹۴
، راشدی
زبان چکیده: استاد راهنما
زبان چکیده: استاد راهنما
زبان چکیده: استاد مشاور
چاپی
کارشناسی ارشد
علوم جغرافیایی گرایش جغرافیای پزشکی
۱۳۹۴/۱۱/۱۸
تبریز
ساری صراف، بهروز
دستگیری، سعید
خامنیان، ژیلا
.Background and Aim: Phenylketonuria (PKU) is a metabolic error which is caused by the deficiency of phenylalanine hydroxylase (PAH) inverting phenylalanine to tyrosine. This disease is the most common form of hyperphenyalaninaemia stow which is inherited in a form of a predominant autosomal. Therefore, the aim of this study is to investigate the distribution of occurrence of phenylketonuria disease in the world and Iran by using the systematic review and meta-analysis. Materials and Methods: The national and international databases such as Google scholar, Medline, Embase per PubMed and OVID, CINAHL, IranDOC, IranMedex, SID, Magiran, have been searched from 1990 onwards, without the language restrictions and by using the key words: phenylketonuria, prevalence, incidence, congenital diseases. 304 articles related with this topic, were found. Quality articles using STROBE Chec list of sectional articles were evaluated. In the finally, 68 study were accepted. Heterogeneity between studies was assessed using the I2 test. The random effects model was used to combine the results together. Data was analyzed by using Comprehensive Meta-Analysis software at 95 confidence level. The distribution of diseases was shown by using Geographic Information System software on Iran and the world map
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مرادی، پرستو
si slevel lanoitanretni dna lanoitan eht ni esaesid eht fo ecnerrucco eht ecuder ot dednemmocer si smargorp lortnoc dna gniniart etairporppa eht fo tnempoleved eht ,eroferehT .siht mrifnoc narI ni enod seiduts tneceR .egareva labolg eht ot derapmoc hgih si seirtnuoc gnirobhgien eht dna narI ni airunoteklynehp fo ecnerrucco eht taht dias eb nac ti ,yduts tnerruc eht ot gnidroccA :noisulcnoC
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