"Under the direction of leading experts in oxidative stress, this book addresses cutting-edge areas of research regarding micronutrients and the brain. It discusses identification of brain-specific micronutrients that support function and molecular mechanisms underlying neuroprotectant activity. The book covers age-related metabolic pathways, mitochondrial nutrients, and neurodegeneration. Additional chapters cover flavonoids, cell signaling, and neuronal functions, as well as the role of choline, amino acids, metals, and other micronutrients in brain health and function. The text places a particular emphasis on lipoic acid, which is shown to be a therapeutic agent in neuropathologies."--Publisher's description.
Neuroprotection after cardiac arrest by avoiding acute hyperoxia and by antioxidant genomic postconditioning / Gary Fiskum and Robert E. Rosenthal -- The neuroprotective role of micronutrients in Parkinson's disease / Kristen Malkus, Elpida Tsika, and Harry Ischiropoulos -- Phytoestrogens and brain health / Liqin Zhao and Roberta Diaz Brinton -- Food antioxidants and Alzheimer's disease / Emma Ramiro-Puig ... [et al.] -- Micronutrient antioxidants, cognition, and neuropathology: a longitudinal study in the canine model of human aging / Wycliffe O. Opii and Elizabeth Head -- Excitatory amino acids, S-nitrosylation, and protein misfolding in neurodegenerative disease: protection by memantine and nitromemantine at NMDA-gated channels / Tomohiro Nakamura and Stuart A. Lipton -- Cognitive and behavioral consequences of iron deficiency in women of reproductive age / Laura E. Murray-Kolb -- Micronutrient needs of the developing brain: priorities and assessment / Anita J. Fuglestad, Sara E. Ramel, and Michael K. Georgieff -- Therapeutics of Alzheimer's disease based on metal bioavailability / Su San Mok and Ashley I. Bush -- Lipoic acid as a novel treatment for mild cognitive impairment and early-stage Alzheimer's disease / Annette Maczurek ... [et al.] -- Zinc and the cytoskeleton in neuronal signaling / Gerardo G. Mackenzie and Patricia I. Oteiza -- Tocotrienol neuroprotection: the most potent biological function of all natural forms of vitamin E / Chandan K. Sen, Savita Khanna, and Sashwati Roy -- Fruits, nuts, and brain aging: nutritional interventions targeting age-related neuronal and behavioral deficits / James A. Joseph, Barbara Shukitt-Hale, and Lauren M. Willis -- Modulation of multiple pathways involved in the maintenance of neuronal function by fisetin / Pamela Maher -- Dietary flavonoids as neuroprotective agents / Jeremy P. E. Spencer ... [et al.] -- Actions of bioactive phytochemicals in cell function and Alzheimer's disease pathology / Richard E. Hartman -- Does ginkgo biloba extract exert an effect on Alzheimer's disease progression / Yves Christen -- Green tea polyphenols protect neurons against Alzheimer's disease and Parkinson's disease / Baou Zhao -- Transport of flavonoids into the brain / Paul E. Milbury -- Prevention and treatment of neurodegenerative diseases by spice-derived phytochemicals / Bharat B. Aggarwal, Kuzhuvelil B. Harikumar, and Sanjit Dey -- Neurohormetic properties of the phytochemical resveratrol / Andrea Lisa Holme and Shazib Pervaiz -- Sirtuin and resveratrol / Antoni Camins ... [et al.] -- Acetyl-l-carnitine and ferulic acid action in aging and neurodegenerative diseases / Rena A. Sowell, Christopher D. Aluise, and D. Allan Butterfield -- Evidence required for causal inferences about effects of micronutrient deficiencies during development on brain health: DHA, choline, iron, and vitamin D / Joyce C. McCann and Bruce N. Ames -- Omega-3 fatty acids and brain function in older people / Ricardo Uauy and Alan D. Dangour -- Iron and monoamine oxidase in brain function and dysfunction: development of neuroprotective-neurorescue drugs / Orly Weinreb ... [et al.] -- Antioxidative defense of brain microglial cells / Ralf Dringen and Johannes Hirrlinger -- Branched-chain amino acids and brain metabolism / Radovan Murin and Bernd Hamprecht.