عنوان

Chemogenomics in drug discovery

352730987X

IR

EB24939

انگلیسی

IR

Chemogenomics in drug discovery

[Electronic Resource]

:a medicinal chemistry perspective

/ edited by Hugo Kubinyi and Gerhard Muller

Weinheim

: Wiley-VCH,

, c2004.

xxiv, 463 p. ill. (some col.) 25 cm.

(Methods and principles in medicinal chemistry

; v. 22)

e

ng

Includes bibliographical references and index.

Target family-directed masterkeyes in chemogenomics /Gehard Muller --Drug discovery from side effects /Hugo Kubinyi --The value of chemical genetics in drug discovery /Keith Russell and William F. Michne --Structural aspects of binding site similarity: a 3D upgrade for chemogenomics /Andreas Bergner and Judith Gunther --The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds /Edgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin --Chemical kinomics /Bert M. Klebl, Henrik Daub, and Gyorgy Keri --Structural aspects of kinases and their inhibitors /Rogier Buijsman --A chemical genomics approach for ion channel modulators /Karl-Heinz Baringhaus and Gerhard Hessler -- Phosphodiesterase inhibitors: a chemogenomic view /Martin Hendrix and Christopher Kallus --Proteochemometrics: a tool for modeling the molecular interaction space /Jarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis --Some principles related to chemogenomics in compound library and template design for GPCRs /Thomas R. Webb --Computational filters in lead generation: targeting drug-like chemotypes /Wolfgang Guba and Olivier Roche --Navigation in chemical space: ligand-based design of focused compound libraries /Gisbert Schneider and Petra Schneider --Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates /Marcus A. Koch and Herbert Waldmann --Combinatorial chemistry in the age of chemical genomics /Reni Joseph and Prabhat Arya.

Pharmaceutical chemistry

Drug development

Pharmacogenetics

Combinatorial Chemistry Techniques

Drug Design

Genomics

Medicaments- Developpement

Chimie pharmaceutique

Medicaments- Recherche

Medicaments- Conception

Kubinyi, Hugo

Muller, Gerhard,1963-

ایران

352730987X.pdf

محرمانه

محرمانه

352730987X.pdf

0

متن

old catalog

e

BL

1

a

Y