عنوان

Drug metabolism concepts :

0841203709

9780841203709

0841203547

9780841203549

b783647

Drug metabolism concepts :

[Book]

a symposium cosponsored by the Division of Medicinal Chemistry and the division of Analytical Chemistry at the 172nd meeting of the American Chemical Society, San Francisco, Calif., August 31, 1976 : [Proceedings] /

Donald M. Jerina, editor.

Washington :

American Chemical Society,

1977.

ix, 196 pages :

illustrations ;

24 cm.

ACS symposium series ;

44,

0097-6156

Includes bibliographical references and index.

Cytochrome P-450 : its role in oxygen activation for drug metabolism / R.W. Estabrook and J. Werringloer -- Synthetic models for the reaction stages of cytochrome P-450 / James P. Collman and Thomas N. Sorrell -- Biochemical studies on drug metabolism : isolation of multiple forms of liver microsomal cytochrome P-450 / M.J. Coon, J.L. Vermilion, K.P. Vatsis, J.S. French, W.L. Dean, and D.A. Haugen -- Resolution of multiple forms of rabbit liver cytochrome P-450 / Eric F. Johnson and Ursula Muller-Eberhard -- Enantiomeric selectivity and perturbation of product ratios as methods for studying the multiplicity of microsomal enzymes / William F. Trager -- Role of purified cytochrome P-448 and epoxide hydrase in the activation and detoxification of benzo[a]pyrene / W. Levin, A.W. Wood, A.Y.H. Lu, D. Ryan, S. West, A.H. Conney, D.R. Thakker, H. Yagi, and D.M. Jerina -- In vitro reactions of the diastereomeric 9,10-epoxides of (+) and ( -- )-trans-7,8-dihydroxy-7,8-dihydrobenzo-[a]pyrene with polyguanylic acid and evidence for formation of an enantiomer of each diastereomeric 9,10-epoxide from benzo[a]pyrene in mouse skin / P.D. Moore, M. Koreeda, P.G. Wislocki, W. Levin, A.H. Conney, H. Yagi, and D.M. Jerina -- Role of metabolic activation in chemical-induced tissue injury / Sidney D. Nelson, Michael R. Boyd, and Jerry R. Mitchell.

0

Drug metabolism concepts.

Benzopyrene-- Metabolism, Congresses.

Carcinogenesis, Congresses.

Cytochrome P-450, Congresses.

Drugs-- Metabolism, Congresses.

Drug Synergism.

Drug Tolerance.

Metabolism-- drug effects.

Pharmaceutical Preparations-- metabolism.

Benzopyrene-- Metabolism.

Carcinogenesis.

Cytochrome P-450.

Drugs-- Metabolism.

Jerina, Donald M., (Donald Michael),1940-

American Chemical Society., Division of Analytical Chemistry.

American Chemical Society., Division of Medicinal Chemistry.

20201206215705.0

[Book]

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