The organism. Historical overview / Walter T. Hughes. Nomenclature and genetic variation of pneumocystis / Scott P. Keely and James R. Stringer. Pneumocystis cellular structure / Eduardo Dei-Cas, El Moukhtar Aliouat, and Jean-Charles Cailliez. Surface antigens / James R. Stringer. Signal transduction and cellular communication / Donald J. Ferguson, Jr. and Alan George Smulian. Transmission and epidemiology / Melanie T. Cushion. Pneumocystis genome project and genomic organization / Melanie T. Cushion, Bradley E. Slaven, and Alan George Smulian -- Host defenses/interaction with the host. The neonatal period / Beth A. Garvy and Mahboob H. Qureshi. Interaction of pneumocystis with alveolar macrophages and epithelial cells / Andrew H. Limper. T cells in defense against pneumocystis / James M. Beck. Cytokines / Judd E. Shellito and Jay K. Kolls. The role of humoral immunity in the defense against pneumocystis / Francis Gigliotti [and others] The pulmonary surfactant system in pneumocystis pneumonia / Michael F. Beers and James M. Beck. Mechanisms of lung injury during pneumocystis pneumonia / Terry W. Wright, Allen G. Harmsen, and Francis Gigliotti -- Infection in humans. Clinical presentation and diagnosis of pneumocystis pneumonia in HIV-infected patients / Laurence Huang. Pneumocystis pneumonitis in non-HIV-infected patients: update / Walter T. Hughes. Pneumocystis jirovecii pneumonia in AIDS patients in the developing world / Powel Kazanjian, David T. Fisk, and Steven R. Meshnick. Immunological features of pneumocystis infection in humans / Peter D. Walzer. Molecular typing and epidemiological insights / Charles Ben Beard. Current regimens for treatment and prophylaxis of pneumocystis jirovecii pneumonia / Hans Henrik Larsen, Henry Masur, and Joseph A. Kovacs. Lipids / Edna S. Kaneshiro. Polyamines, iron, and pneumocystis carinii / Allen B. Clarkson, Jr. and Salim Merali. DHFR and IMPDH: enzymes exploitable as drug targets in pneumocystis / Sherry F. Queener. Dihydropteroate synthase and cytochrome B: the problem of emerging resistance / Steven R. Meshnick and Powel Kazanjian. Development of candidate anti-pneumocystis drugs: in vitro and in vivo approaches / Melanie T. Cushion and Peter D. Walzer.
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"Continuing to serve as the definitive source on the subject, this reference offers a detailed update on the biology, pathogenesis, genetics, and immunology of Pneumocystis - offering invaluable research and previously unpublished findings for both scientists and clinicians studying opportunistic infections associated with HIV and other disorders." "Provides in-depth reviews on the development of new drugs, insights into host-pathogen interactions, emerging diagnostic techniques, global perspectives of the infection, additional susceptible populations, and future directions in the field."--BOOK JACKET.