Influence of the biospecificity of human milk -- Influence of the maternal anatomy and physiology on lactation -- Influence of the infant's anatomy and physiology -- Influence of peripartum factors, birthing practices, and early caretaking behaviors -- First 24-48 hours : common challenges -- Beyond the initial 48-72 hours : infant challenges -- Physical, medical, and environmental problems and issues -- Maternal pathology : breast and nipple issues -- Physical, medical, emotional, and environmental challenges to the breastfeeding mother.