عنوان

Glucokinase and glycemic disease :

1417564911

3318010804

9781417564910

9783318010800

3805577443

9783805577441

b720343

Glucokinase and glycemic disease :

[Book]

from basics to novel therapeutics /

volume editors, F.M. Matschinsky, M.A. Magnuson.

New York :

Karger,

2004.

1 online resource (ix, 406 pages) :

illustrations.

Frontiers in diabetes,

v. 16

0251-5342 ;

Includes bibliographical references and indexes.

Preface / Matschinsky, F.M.; Magnuson, M.A. -- Chapter 1. Background -- Glucokinase as a Glucose Sensor : Past, Present and Future / Magnuson, M.A.; Matschinsky, F.M. -- The Hexokinase Gene Family / Wilson, J.E. -- Comparative Biochemistry of Glucokinase / Cardenas, M.L. -- Chapter 2. Human Biomedical Studies -- Maturity Onset Diabetes of the Young Type 2 / Velho, G. [and others] -- Permanent Neonatal Diabetes mellitus due to Glucokinase Deficiency / Njolstad, P.R. [and others] -- Glucokinase-Linked Hypoglycemia : Clinical Aspects of Activating Glucokinase Mutations / Christesen, H.B.T. [and others] -- Glucokinase and the Regulation of Blood Sugar : A Mathematical Model Predicts the Threshold for Glucose Stimulated Insulin Release for GCK Gene Mutations that Cause Hyper- and Hypoglycemia / Gloyn, A.L. [and others] -- Glucokinase/Glutamate Dehydrogenase Interactions in the GDH form of Congenital Hyperinsulinism / Kelley, A.; Li, C.; Stanley, C.A. -- Chapter 3. Structure and Function -- Glucokinase : A Monomeric Enzyme with Positive Cooperativity / Cornish-Bowden, A.; Cardenas, M.L. -- Molecular Models of Human Glucokinase and the Implications for Glycemic Diseases / Harrison, R.W.; Weber, I.T. -- Crystal Structure of Human Liver Glucokinase Bound to a Small Molecule Allosteric Activator : Insights into the Activating Mutations / Dunten, P. [and others] -- Chapter 4. Regulation of Glucokinase -- Molecular Biology of Glucokinase Regulation / Iynedjian, P.B. -- Role of the Transcription Factor Sterol Regulatory Element Binding Protein-1c in Hepatic Glucokinase Gene Regulation / Foufelle, F.; Ferre, P. -- Regulation of Hepatic Glucokinase Gene Expression / Postic, C.; Decaux, J.-F.; Girard, J. -- Discovery and Role of Glucokinase Regulatory Protein / van Schaftingen, E.; Veiga da Cunha, M. -- GKRP/GK: Control of Metabolic Fluxes in Hepatocytes / Agius, L. [and others] -- Regulation of Glucokinase as Islets Adapt to Pregnancy / Sorenson, R.L.; Weinhaus, A.J.; Brelje, T.C. -- Regulation of Glucokinase by Vitamins and Hormones / Fernandez-Mejia, C.; German, M.S. -- Regulation of [beta]-Cell GK Gene Transcription by Insulin / Leibiger, B.; Berggren, P.-O.; Leibiger, I.B. -- Interaction of GK with the Bifunctional Enzyme 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (6PF2K/F26P2ase) / Baltrusch, S. [and others] -- Role of Sulfhydril Groups in GK Catalysis for GK Function / Tiedge, M.; Baltrusch, S.; Lenzen, S. (Hannover) -- Chapter 5. Tissue-Specific Functions -- Mouse Models of Altered Glucokinase Gene Expression / Magnuson, M.A.; Kim, K.-A. -- Anatomy, Physiology and Regulation of Glucokinase as a Brain Glucosensor / Levin, B.E. [and others] -- A Glucokinase/AP-1 Glucose Transduction Mechanism in the Ventromedial Hypothalamic Satiety Center / Yang, X.-j. [and others] -- The Hepatoportal Glucose Sensor : Mechanisms of Glucose Sensing and Signal Transduction / Thorens, B. -- Linear Relationship between Glucokinase Expression, Metabolic Redox State and Insulin Secretion / Piston, D.W.; Patterson, G.H. -- Glucokinase in [beta]-Cell Insulin-Secretory Granules / Miwa, I.; Toyoda, Y.; Yoshie, S.-- Chapter 6: Glucokinase as Drug Target -- Discovery and Actions of Glucokinase Activators / Grimsby, J.; Matschinsky, F.M.; Grippo, J.F. -- Balancing Hepatic Glucose Disposal and Production : Key Regulatory Genes and Therapeutic Opportunities / Yang, R.; Newgard, C.B.

0

Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.

S. Karger AG

978-3-318-01080-0

Glucokinase and glycemic disease.

3805577443

Diabetes.

Glucokinase.

Glucokinase-- metabolism.

Glucokinase-- secretion.

Glucokinase-- therapeutic use.

Glucose Metabolism Disorders-- metabolism.

Glucose Metabolism Disorders-- therapy.

Models, Molecular.

Diabète.

Glucose-- Métabolisme.

Hexokinase.

Diabetes mellitus-- Pharmakotherapie, Aufsatzsammlung.

Diabetes.

Glucokinase-- Physiologie, Aufsatzsammlung.

Glucokinase.

HEALTH & FITNESS-- Diseases-- Diabetes.

Pharmakotherapie-- Diabetes mellitus, Aufsatzsammlung.

HEA-- 039050

RC

Magnuson, M. A., (Mark A.)

Matschinsky, F. M., (Franz M.)

20201208120652.0

pn

[Book]

Y