Toxicological Effects of Methylmercury -- Copyright -- PREFACE -- Contents -- EXECUTIVE SUMMARY -- THE CHARGE TO THE COMMITTEE -- THE COMMITTEE'S APPROACH TO ITS CHARGE -- THE COMMITTEE'S EVALUATION -- Health Effects of Methylmercury -- Determination of the Critical Study for the RfD -- Estimation of Dose and Biological Variability -- Modeling the Dose-Response Relationships -- Public-Health Implications -- RESEARCH NEEDS -- RECOMMENDATIONS -- 1 INTRODUCTION -- SOURCES OF HG -- FATE AND TRANSPORT -- HEALTH EFFECTS -- EXPOSURE EVENTS AND STUDIES
CONCLUSIONSRECOMMENDATIONS -- REFERENCES -- 4 DOSE ESTIMATION -- DIETARY ASSESSMENT -- BIOMARKERS OF EXPOSURE -- Methylmercury in Blood -- Methylmercury in Hair -- Comparison of Biomarkers of Exposure -- ANALYTICAL ERROR IN BIOMARKER MEASUREMENTS -- EXPOSURE AND DOSE ASSESSMENT IN THE SEYCHELLES, FAROE ISLANDS, AND NEW ZEALAND STUDIES -- SUMMARY AND CONCLUSIONS -- RECOMMENDATIONS -- REFERENCES -- 5 HEALTH EFFECTS OF METHYLMERCURY -- CARCINOGENICITY -- Human Studies -- Animal Studies -- GENOTOXICITY -- Human Studies -- Animal Studies
In Vitro StudiesIMMUNOTOXICITY -- Human Studies -- Animal Studies -- Effects on the Adult Immune System -- Effects on the Developing Immune System -- In Vitro Studies -- Autoimmune Response -- Human Studies -- Animal Studies -- REPRODUCTIVE EFFECTS -- Human Studies -- Animal Studies -- RENAL TOXICITY -- Human Studies -- Animal Studies -- CARDIOVASCULAR EFFECTS -- Human Studies -- Animal Studies -- HEMATOLOGICAL EFFECTS -- DEVELOPING CENTRAL-NERVOUS-SYSTEM TOXICITY -- Human Studies -- High-Dose Poisonings -- Poisoning Episode in Japan
SUMMARY OF RISK ASSESSMENTS FOR MEHGSCIENTIFIC CONTROVERSIES AND SOURCES OF UNCERTAINTY -- ORGANIZATION OF THE REPORT -- REFERENCES -- 2 CHEMISTRY, EXPOSURE, TOXICOKINETICS, AND TOXICODYNAMICS -- PHYSICAL AND CHEMICAL PROPERTIES -- METHODS OF CHEMICAL ANALYSIS -- EXPOSURES TO MEHG IN THE U.S. POPULATION -- TOXICOKINETICS -- Absorption and Distribution -- Methylmercury -- Dimethylmercury -- Elemental Mercury -- Inorganic Mercury -- Biotransformation -- Excretion -- MOBILIZATION OF BODY HG -- CHEMICAL FORMS OF HG IN TOXICITY
TOXIC EFFECTS AND TARGET ORGANSBIOCHEMICAL MECHANISMS OF TOXICITY -- SUMMARY AND CONCLUSIONS -- RECOMMENDATIONS -- REFERENCES -- 3 BIOLOGICAL VARIABILITY -- AGE-RELATED SUSCEPTIBILITY -- GENDER DIFFERENCES -- GENETICS -- MECHANISMS OF NUTRITIONAL INFLUENCE ON MEHG HEALTH EFFECTS -- Dietary Interactions and Confounding -- Selenium -- Garlic -- Omega-3 Fatty Acids -- Protein -- Alcohol -- Other Foods That Might Influence Hg Uptake -- Vitamin E -- Nutrient Enhancement of Toxicity -- Beneficial Effects of Fish Consumption -- TOXICOKINETIC VARIABILITY
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Annotation
00017961
Toxicological Effects of Methylmercury.
9780309071406
Methylmercury-- Toxicology.
Mercury-- toxicity.
Methylmercury Compounds-- toxicity.
Methylmercury-- Toxicology.
615
.
902
RA1231
.
M5
.
T695
2000eb
Staff, National Research Council.
Methylmercury, Committee on the Toxicological Effects of.
Staff, Board on Environmental Studies and Toxicology.