عنوان

Drosophila models for human diseases /

9789811305290

9811305293

9789811305283

9811305285

Drosophila models for human diseases /

[Book]

Masamitsu Yamaguchi, editor.

Singapore :

Springer,

[2018]

©2018

1 online resource (x, 308 pages) :

illustrations (some color)

Advances in experimental medicine and biology,

volume 1076

2214-8019 ;

Includes bibliographical references and index.

Drosophila as a model organism / Masamitsu Yamaguchi, Hideki Yoshida -- Adult intestine aging model / Koji Takeda, Takashi Okumura, Kiichiro Taniguchi, Takashi Adachi-Yamada -- Alzheimer's disease model system using drosophila / Leo Tsuda, Young-Mi Lim -- Parkinson's disease model / Vuu My Dung, Dang Thi Phuong Thao -- Repeat expansion disease models / Morio Ueyama, Yoshitaka Nagai -- Amyotrophic lateral sclerosis model / Yumiko Azuma, Ikuko Mizuta, Takahiko Tokuda, Toshiki Mizuno -- Drosophila Charcot-Marie-Tooth disease models / Masamitsu Yamaguchi, Hiroshi Takashima -- Drosophila as a model to gain insight into the role of lncRNAs in neurological disorders / Luca Lo Piccolo -- Muscular dystrophy model / Saranyapin Potikanond, Wutigri Nimlamool, Jasprien Noordermeer, Lee G. Fradkin -- Drosophila as a cancer model / Masato Enomoto, Carmen Siow, Tatsushi Igaki -- From drosophila blood cells to human leukemia / Manon Boulet, Marion Miller, Laurence Vandel, Lucas Waltzer -- Diseases associated with mutation of replication and repair proteins / Sue Cotterill -- Drosophila models to investigate insulin action and mechanisms underlying human diabetes mellitus / Yoshihiro H. Inoue, Hiroka Katsube, Yukiko Hinami -- Metabolomics: state-of-the-art technologies and applications on Drosophila melanogaster / Phan Nguyen Thuy An, Eiichiro Fukusaki -- Humanized flies and resources for cross-species study / Toshiyuki Takano-Shimizu-Kouno, Takashi Ohsako -- Designs for flies + of mice and men: design approaches to Drosophila melanogaster / Julia Cassim, Frank Kolkman, Marcel Helmer.

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"Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila. This volume provides recent advances in Drosophila models for various human diseases, with each chapter providing a review of studies involving Drosophila models, as well as detailed protocols commonly used in laboratories. Starting with a review of Drosophila's value as a highly tractable model organism for studying human diseases, subsequent chapters present Drosophila models for specific human diseases. The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases"--Publisher's description.

Springer Nature

com.springer.onix.9789811305290

Drosophila models for human diseases.

9789811305283

Diseases-- Animal models.

Drosophila.

Disease Models, Animal.

Drosophila.

Humans.

Diseases-- Animal models.

Drosophila.

HEALTH & FITNESS-- Diseases-- General.

MEDICAL-- Clinical Medicine.

MEDICAL-- Diseases.

MEDICAL-- Evidence-Based Medicine.

MEDICAL-- Internal Medicine.

HEA-- 039000

MED-- 014000

MED-- 022000

MED-- 045000

MED-- 112000

MFN

Yamaguchi, Masamitsu

20200823223853.0

pn

[Book]

Y