Intro; Preface; Abbreviations; Contents; 1: The Nexus of Development and Environment; References; Part I: Plasticity in Developmental and Evolutionary Time and Space; 2: The Interaction of Environment and Chronological and Developmental Time; 2.1 Overview; 2.1.1 Plasticity and Development; 2.1.2 Developmental Model Systems; 2.1.3 Novel Organisms: Working Beyond Traditional Models; 2.1.4 Setting the Stage; 2.2 Developmental Timing; 2.2.1 Heterochrony; 2.2.1.1 Timing Mechanisms; 2.2.1.2 Examples of Alteration of Somitogenesis; 2.2.1.3 Heterochronic Genes and Disease.
2.2.1.4 Physiological Heterochrony2.2.1.5 Sequence Heterochrony; 2.2.1.6 Population-Level Heterochrony; 2.2.2 Heterokairy; 2.3 Developmental Time: Practical Considerations; 2.3.1 Developmental Rate and Chronological Time; 2.3.2 Developmental Time and Experimental Planning; 2.3.3 Developmental Time and Physiology; 2.3.4 Developmental Time and Model Organisms; References; 3: Critical Windows in Animal Development: Interactions Between Environment, Phenotype, and Time; 3.1 Introduction; 3.1.1 Definition and History of Developmental Critical Windows.
3.1.2 Critical Windows Are Central to the Interaction Between Development, Physiology, and Environment3.2 Stage-Specific Sensitivity to Naturally Occurring Environmental Stressors; 3.2.1 Respiratory Gases; 3.2.2 Temperature; 3.2.2.1 Temperature-Dependent Sex Determination; 3.2.3 Salinity; 3.2.4 Pathogens; 3.3 Critical Windows for Exposure to Environmental Contaminants; 3.3.1 Ethanol; 3.3.2 Heavy Metals; 3.3.3 Endocrine Disrupting Chemicals; 3.3.4 Sensitivity of Embryo Versus Larval Stages; 3.4 Considerations for Critical Window Experimental Approaches.
3.4.1 Length of Exposure and Overlapping Exposures3.4.2 Stressor Doses; 3.4.3 Systems Approach to Critical Windows; 3.4.4 Combined Stressors; 3.4.5 Timing of Endpoint Measurement; References; 4: Developmental Plasticity and Heterokairy; 4.1 Introduction; 4.2 Phenotypic Plasticity, Developmental Plasticity and Heterokairy; 4.2.1 Phenotypic Plasticity; 4.2.2 Developmental Plasticity; 4.2.3 Heterokairy; 4.2.3.1 Is Heterokairy a Way of Integrating Disparate but Parallel Literatures that Investigate Altered Timing During Development?; Developmental Transitions in Plants and Animals.
Environmental Modification of Developmental TransitionsTesting Ideas from the Evo-Devo Community; Heterokairy Is a Way of Integrating Disparate but Parallel Research Interests; 4.2.3.2 Evaluating Current Explicit Investigations of Heterokairy; Reintegration of Development, Evolution and Physiology; Explicit Studies of Heterokairy; Nested Hierarchy Hypothesis; Adaptive Plasticity and Flexible Stem Hypotheses; 4.2.3.3 Heterokairy and Adaptive Evolution; 4.2.3.4 Heterokairy and Global Environmental Change; 4.3 Heterokairy: The 'Big Picture'; References.
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Rather than a loosely connected list of facts/topics, this book addresses virtually every field that involves the use of developing animals in environmental science. In doing so, it will help define the scientific collective within these fields to both those readers who are "outside" of a particular field (students and professionals alike) and those who work within said field, where multiple iterations of the same job description exist. Both the content and choice of authors fully support this goal, as the editors and contributing authors represent contemporary thought and experimentation in their respective fields - ranging from developmental physiology through environmental toxicology to medicine. As such, this work will appeal to a broad audience, including any scientist or trainee interested in the nexus of environment, development and physiology.