Meningiomas of the Skull Base: Treatment Nuances in Contemporary Neurosurgery; Title Page; Copyright; Dedication; Contents; Foreword; Preface; Contributors; Abbreviations; 1 Introduction; 1.1 Essential ""Arrows"" in the Technical Quiver: Fragments of Personal Memoirs; 1.2 Imaging (1973); 1.2.1 The Operating Microscope (1955); 1.2.2 Modern Endoscopy (1974); 1.2.3 Imaging Directed Stereotaxy and Navigation (1977); 1.2.4 Bipolar Forceps (1955); 1.2.5 Ultrasonic Aspirator (1978); 1.2.6 Microanatomy (1973); 2 The Evolution of Surgery-the Soul of Neurosurgery; 2.1 Introduction: Early History
2.2 Nomenclature2.3 Stages of Surgery for Meningiomas; 2.4 Initial Surgical Progress; 2.5 Extracranial Approaches to Skull Base Lesions; 2.6 Microneurosurgery; 2.7 Refined Skull Base Approaches and Anatomical Studies; 2.8 Allied Advances in Meningioma Management; 2.9 Modern Surgical Management; References; 3 Inside the Pathology; 3.1 Skull Base: Elements of Anatomy and Embryology; 3.2 Surgical Resectability; 3.3 Meningiomas; 3.3.1 Definition and Epidemiology; 3.3.2 Histopathology; 3.3.3 Immunohistochemistry; 3.3.4 Molecular Features; 3.3.5 Prognostic Factors
3.4 Solitary Fibrous Tumor/Hemangiopericytoma3.5 Meningiomas of the Skull Base; 3.5.1 Skull Base Meningiomas in Pediatric Age; 3.6 Future Perspectives; References; 4 Exogenous Factors Affecting Meningiomas; 4.1 Introduction; 4.2 Ionizing Radiation; 4.3 Exogenous Hormones; 4.3.1 Link between Cyproterone Acetate and Meningiomas; 4.4 Radiofrequency Electromagnetic Fields; 4.5 Metabolic Syndrome and Obesity; 4.6 Occupational Exposures; 4.7 Smoking; 4.8 Immunity; 4.9 Trauma; 4.10 Conclusion; References; 5 Instrumentation (Micro, Endo, IGS, MRI Application); 5.1 Introduction
5.2 The Role of the Microscopy in Skull Base Surgery5.2.1 Positioning; 5.2.2 Operating Microscope; 5.2.3 Microsurgical Instruments and Techniques; 5.3 Endoscopy; 5.3.1 Introduction; 5.3.2 The Endoscope; 5.3.3 Pure Endoscopic Approaches; 5.3.4 Endoscope-Assisted Microneurosurgery; 5.4 Image-Guided Surgery; 5.5 Reconstruction Materials; 5.5.1 Duraplasty and Hemostasis; References; 6 Intraoperative Neurophysiologic Monitoring during Surgery; 6.1 Introduction; 6.2 Intraoperative Neurophysiologic Monitoring Techniques; 6.2.1 Mapping Techniques to Identify Cranial Motor Nerves
6.2.2 Monitoring Techniques6.2.3 Anesthetic Considerations; 6.3 Clinical Application in Skull Base Surgery; 6.3.1 IONM for Sellar and Cavernous Sinus Surgery; 6.3.2 IONM for Cerebellopontine Angle Surgery; 6.3.3 IONM for Jugular Foramen-Clival and Foramen Magnum Surgery; 6.4 IONM Changes and Surgical Strategy; 6.5 Conclusions; References; 7 Role of Stereotactic Radiosurgery; 7.1 Introduction; 7.2 Radiobiology of Skull Base Meningiomas; 7.3 Outcomes of Stereotactic Radiosurgery for Skull Base Meningiomas; 7.3.1 Radiological Response; 7.3.2 Cranial Neuropathy; 7.3.3 Brainstem Toxicity
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Meningiomas, the second most frequent of intracranial tumors, are characterized by a protean range of possible locations and appearances, due to their origin from the extensive and intricately formed meninges. As such, a wide variety of differential diagnoses is typical, and the therapies chosen are necessarily highly variable. The introductory chapters of this book cover the pathology of these tumors, the evolution of special surgical methods, instrumentation, intraoperative monitoring, and the role of radiosurgery. Ten surgical chapters cover the individual regions of occurrence, including ...