3.2 The Past: The Role of Histology and Radiology3.3 The MDT; 3.4 Composition of MDT; 3.5 MDT Diagnosis Is Influenced by Components; 3.6 Final Scope of MTD; 3.6.1 Comparison Between Cryobiopsy and Surgical Biopsy in MDT Discussion; 3.7 Conclusion; References; Part II: Transbronchial Cryobiopsy; 4: Cryobiopsy: Physics; 4.1 Introduction: Cold Temperatures in Lung Diseases; 4.2 Physic Principle of TBLC; 4.3 "Joule-Thomson" Effect in TBLC; 4.3.1 Cryogenic Gases; 4.3.2 Tissue Cryosensitivity; 4.3.3 Probes; 4.3.4 Activation of the Probe; 4.3.5 Thawing Phase
4.4 The "Joule-Thomson" Effect on Living Tissues: Mechanism of Tissue DamageReferences; 5: Technique and Equipment in Transbronchial Cryobiopsy; 5.1 Introduction; 5.2 A Summary of What TBLC Needs to Be Carried Out; 5.3 Sedation/Anaesthesia; 5.4 Airway Management; 5.5 Patient Ventilation; 5.6 Bronchial Blockers; 5.7 Fluoroscopic Guidance; 5.8 Cryogenic Gases; 5.9 Cryoprobes; 5.10 Where to Take a TBLC and How Many Samples Should Be Taken; 5.11 How to Manage the TBLC Samples; 5.12 Learning Curve
5.13 What Happens After the Biopsy: Writing the Report, Post-procedural Monitoring and Management of ComplicationsReferences; 6: Complications of Transbronchial Cryobiopsy; References; 7: Histology for Transbronchial Lung Cryobiopsy Samples; 7.1 Introduction; 7.1.1 Processing of Cryobiopsy Specimens; 7.1.2 Normal Structure of the Lobules and Acini in TBLC Specimens; 7.1.3 Pathological Diagnosis of UIP Based on the Pulmonary Architecture; 7.1.3.1 UIP Diagnosed in SLB Specimens; 7.1.3.2 UIP Diagnosed in TBLC Specimens; 7.2 Conclusion; References
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This book presents both theoretical and practical aspects of transbronchial cryobiopsy, a new diagnostic technique for the detection of diffuse parenchymal lung disease that is attracting great interest in the scientific community. In the context of a multidisciplinary discussion, comprising radiologic-pathologic correlations, the authors examine the technical and safety issues - such as equipment, endoscopic setting, anesthesiologic approaches and bleeding control - on one hand, and the diagnostic yield and clinical meaning on the other. The volume offers several case studies - including idiopathic pulmonary fibrosis, granulomatous disorders, interstitial pneumonias, rare lung disseminated tumors- that illustrate the high diagnostic yield and safety of this innovative technique. The book appeals to a wide readership, including residents, pulmonologists with expertise in diffuse parenchymal lung diseases, interventional pulmonologists, thoracic radiologists, pathologists, anesthesiologists, internists and rheumatologists.
Springer Nature
com.springer.onix.9783030148911
Transbronchial cryobiopsy in diffuse parenchymal lung disease.