عنوان

Cytochromes c :

3642745369

9783642745362

b573296

Cytochromes c :

[Book]

Evolutionary, Structural and Physicochemical Aspects

by Geoffrey R. Moore, Graham W. Pettigrew.

Berlin, Heidelberg

Springer Berlin Heidelberg

1990

(xvi, 478 pages 149 illustrations)

Springer series in molecular biology.

1 Stereochemical and Physicochemical Properties of Hernes --; 1.1 Introduction --; 1.2 Electronic Structure of Iron --; 1.3 Stereochemistry of Metalloporphyrins --; 1.4 Properties of Ligands --; 1.5 Metal-free and Metal-substituted Cytochrome c --; 2 Spectroscopic Studies of Cytochromes --; 2.1 Introduction --; 2.2 Spectroscopic Methods --; 2.3 Selected Applications of Spectroscopy to Cytochromes c --; 3 Amino Acid Sequences of Cytochromes c --; 3.1 Introduction --; 3.2 Amino Acid Sequences of Mitochondrial Cytochromes c --; 3.3 Amino Acid Sequences of Cytochromes c1 and Cytochromes f --; 3.4 Amino Acid Sequences of Cytochromes c2 --; 3.5 Amino Acid Sequences of Cytochromes c3 --; 3.6 Amino Acid Sequences of Cytochromes c4 --; 3.7 Amino Acid Sequences of Cytochromes c5 --; 3.8 Amino Acid Sequences of Cytochromes c-555 --; 3.9 Amino Acid Sequences of Cytochromes c6 (algal cytochrome 'c-553') --; 3.10 Amino Acid Sequences of Cytochromes c-551 (Cytochromes c7) --; 3.11 Amino Acid Sequences of Class II Cytochromes c (Cytochromes c8) --; 3.12 Cytochrome c Peroxidase --; 3.13 The Reaction Centre Cytochrome from Rhodopseudomonas viridis --; 3.14 Amino Acid Sequences of Cytochromes c Which Do Not Fall Into the Established Sequence Classes --; 4 The Structures of Class I Cytochromes c --; 4.1 Introduction --; 4.2 General Features of the Structure of Mitochondrial Cytochrome c --; 4.3 The Cytochrome Fold and Bacterial Class I Cytochromes --; 4.4 pH Dependent Transitions of Cytochromes c --; 4.5 Differences in Conformation and Dynamics between Reduced and Oxidised Cytochrome c --; 4.6 Structural and Functional Effects of Chemical Modifications on Mitochondrial Cytochrome c --; 5 The Structures of Class II, Class III and Class IV Cytochromes c --; 5.1 Introduction --; 5.2 Class II Cytochromes c --; 5.3 Class III Cytochromes c --; 5.4 Class IV Cytochromes c --; 6 Evolution --; 6.1 Introduction --; 6.2 Aspects of Taxonomy --; 6.3 The Construction of Phylogenetic Trees --; 6.4 The Problems and Successes of Molecular Phylogeny --; 6.5 Neutral Mutation and Natural Selection in the Evolution of Cytochrome c --; 6.6 Gene Duplication, Gene Fusion and Pseudogenes --; 6.7 Lateral Gene Transfer --; 6.8 The Concepts of Genus and Species in Bacteria --; 6.9 Endosymbiotic Origin for Eukaryotic Organelles --; 6.10 Remote Relationships --; 7 Redox Potentials --; 7.1 Introduction --; 7.2 Ligand Binding --; 7.3 The Coordination Structure of the Metal Ion --; 7.4 Electrostatic Influences on Redox Potential --; 7.5 Multiple Redox Centres --; 7.6 Proton Binding --; 7.7 Conformational Stabilisation --; 8 Electron-Transfer Mechanisms --; 8.1 Introduction --; 8.2 General Aspects of Electron Transfer --; 8.3 Theoretical Considerations of Electron Transfer --; 8.4 Self-Exchange Reactions of Cytochromes c --; 8.5 Cross-Reactions of Cytochromes c --; References.

Cytochromes c are haemoproteins which carry out electron transfer in a wide variety of biological systems, necessitating different kinds of cytochrome c to fulfill different biological roles. The evolutionary relationship between cytochromes c and their host organisms are described, as well as their structural, spectroscopic and redox properties, including both electron-transfer rates and redox potentials. The treatment is aimed at the non-specialist so that both the techniques described and their application to cytochromes c can be understood. All classes of cytochrome c are dealt with to provide a comprehensive account of the field. No other text provides such a broad survey. Similar to the earlier volume "Cytochromes c: Biological Aspects" which deals with the classification, biosynthesis and biological role of cytochromes c, the present book is aimed at research workers and advanced students.

Biochemistry.

Cytology.

Life sciences.

by Geoffrey R. Moore, Graham W. Pettigrew.

Geoffrey R Moore

Graham W Pettigrew

[Book]

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