عنوان

Cardiac glycosides

0387086927

3540086927

9780387086927

9783540086925

b558289

Cardiac glycosides

[Book]

ed. by G. Bodem and H.J. Dengler.

Berlin

Springer-Verlag

1978

XIII, [1], 426 s. : il. ; 25 cm.

International Boehringer Mannheim Symposia.

S. red.: International Symposium, Bonn, Germany, January 27-29, 1977.

1 Evaluation of Different Methods for Determining Serum Concentrations of Cardiac Glycosides.- 2 A New Simple Assay for Determining Digoxin Serum Levels.- 3 Chloroform-Extractable and Polar Metabolites Examined With Different Assays.- 4 Studies of the Metabolism of Digoxin and Digitoxin Using Double Isotope Dilution Derivative Methods.- 5 Occurence and Chemical Nature of Polar Water-Soluble Digoxin Metabolites.- 6 Pharmacokinetics and Metabolism of Digitoxin in the Human.- 7 Dihydrodigitoxin, a Metabolite of Digitoxin in Humans.- 8 Enterohepatic Circulation of Digitoxin Metabolites in the Dog.- 9 ?-Methyl-Digoxin, a New Lipophilic Digoxin Derivative.- 10 Tissue Distribution of Cardiac Glycosides.- 11 Plasma-Tissue Distribution of Different Cardiac Glycosides.- 12 Significance of Plasma Concentration of Digoxin in Relation to the Myocardial Concentration of the Drug.- 13 Influence of Thyroid Function on the Pharmacokinetics of Cardiac Glycosides.- 14 Effect of Jejunoileal Bypass on the Bioavailability of Digoxin in Man.- 15 Bioavailability of Digoxin in Renal Insufficiency and Heart Failure.- 16 Bioavailability Studies: Their Influence on the Clinical Use of Digitalis.- 17 Comparative Pharmacokinetics of Various Digoxin Preparations in Man.- 18 Digoxin Pharmacokinetics and Their Relation to Clinical Dosage Parameters.- 19 Clinical Interpretation of Serum Concentrations of Cardiac Glycosides.- 20 Assessment of Digoxin Action by a Pharmacodynamic Biochemical Method.- 21 Relationships Between Doses, Plasma Levels and Cardiac Effects Under Digitalis Treatment.- 22.1 Therapeutic Implications of Digoxin Kinetics in Impaired Renal Function.- 22.2 Peak Plasma Digoxin Concentration and Cardiotoxicity.- 22.3 Biliary Excretion of ?-Acetyl-Digoxin in Man.- 23 Digitoxin Pharmacokinetics in Patients With Renal Disease.- 24 Increased Digitalis Tolerance in Uremic Patients.- 25 Digitoxin and Digoxin in Patients With Chronic Renal Failure and on Hemodialysis.- 26 International Patterns of Clinical Use and Toxicity of Digitalis Glycosides: Report From the Boston Collaborative Drug Surveillance Program.- 27 Pharmacokinetic and Clinical Effects During the Predistribution Phase of Digoxin Treatment.- 28 Digitalis Intoxication: Clinical and Experimental Work.- 29 Digitalis Intoxication: Specificity of Clinical and Electrocardiographic Signs.- 30 Treatment of Digitalis Intoxication.- 31 Biologic Effects of Specific Antibodies in Reversing the Pharmacologic and Toxic Effects of Digoxin.- 32 Reversal of Digitoxin Toxicity and Modification of Pharmacokinetics by Specific Antibodies.- 33 ?-Methyl-Digoxin Disposition During Spironolactone Treatment.- 34 Digitoxin Disposition Under Rifampicin Treatment.- 35 Is There a Need for New Cardiac Glycosides? For More Blood Level Determinations?.

ed. by G. Bodem and H.J. Dengler.

Günter Bodem

Hans J Dengler

[Book]

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