عنوان

Growth Factors and the Ovary.

1468456881

9781468456882

b552298

Growth Factors and the Ovary.

[Book]

Hirshfield, Anne N.

Springer Verlag

2012

I. Ontogeny of the Ovary.- 1. Mesenchymal-Epithelial Interactions in the Growth and Development of the Urogenital Tract.- 2. Overview of Embryological and Fetal Development of the Ovary and Testis.- 3. Role of Second Messengers in Early Differentiation of Gonads and Sex Ducts.- 4. Ovarian Tumors, Stem Cells and Ontogeny: Imminentes Cognitiones.- II. Keynote Speakers.- 5. Growth Factors, Proto-Oncogenes and the Control of Cell Proliferation: Lessons from the Fibroblast.- 6. Molecular Characterization of Fibroblast Growth Factor and Possible Role in Early and Late Embryonic Development.- III. Growth Factors and the Ovary.- 7. Rodent Studies on the Potential Relevance of Insulin-Like Growth Factor (IGF-I) to Ovarian Physiology.- 8. Insulin-Like Growth Factors (IGFs) as Autocrine/Paracrine Regulators in the Porcine Ovarian Follicle.- 9. Regulatory Actions of the Insulin-Like Growth Factor, IGF-I (Somatomedin-C), on Sterol Metabolism by Ovarian Cells.- 10. Growth Factor-Gonadotropin Interactions in Ovarian Cells.- 11. Transforming Growth Factor Production and Action in the Ovarian Follicle: Theca Cell-Granulosa Cell Interactions.- 12. Fibroblast Growth Factors as Local Mediators of Gonadal Function.- IV. Poster Presentation Manuscripts.- 13. Analysis of Binding Sites for IGF-I on Membranes from Granulosa Cells of Small, Medium, and Large Porcine Follicles.- 14. Binding Sites for IGF-I Identified on Theca Cells from Large Porcine Follicles.- 15. The Role of Insulin-Like Growth Factors in Granulosa Cell Steroidogenesis: Studies with a Neutralizing Antibody to IGF-I.- 16. Insulin-Like Growth Factor-I Regulates ?5-3?-Hydroxysteroid Dehydrogenase Activity in Rat Granulosa Cells.- 17. Steroidogenic Effect of Insulin May Not Be Mediated Through Somatomedin-C/IGF-I Receptors.- 18. Insulin-Like Growth Factor-I and Transforming Growth Factor-? Regulate the Differentiation of Purified Ovarian Theca-Interstitial Cells in Serum-Free Medium.- 19. Bovine Thecal Cells Secrete Transforming Growth Factor ? and ?.- 20. Variations in the Level of Transforming Growth Factor-Alpha (TGF?) mRNA During the Human Menstrual Cycle.- 21. Transforming Growth Factor-? Inhibits the LH-Induced Maturation of Rat Oocytes.- 22. Light and Electron Microscope Immunocytochemical Localization of Epidermal Growth Factor Receptors in Bovine Corpora Lutea of Pregnancy.- 23. Maturation of the Oocyte-Cumulus Cell Complex in Mice: Specificity of Epidermal Growth Factor Activity.- 24. Multifactorial Regulation of Granulosa Cell (GC) Proliferation: Interactions Among Polypeptide Growth Factors.- 25. Gonadotropins Enhance the Cytoplasmic Maturation of Mouse Oocytes Under the Influence of Growth Factors.- 26. Initial Characterization of a Luteal Growth Factor for Ovarian Mesothelial Cells.- 27. Gap Junctions in Transformed Rat Granulosa Cells.- 28. PMSG Induction of C-Fos and C-Myc Proteins Within Granulosa Cells of Immature Rat Ovaries.- 29. E-Cadherin May Be Involved in Mediating FSH-Stimulated Responses in Rat Granulosa Cells.- 30. In Vitro Secretion of Angiogenic Activity by Ovine Follicles.- 31. Localization of Tumor Necrosis Factor (TNF) in the Rat and Bovine Ovary Using Immunocytochemistry and Cell Blot: Evidence for Granulosal Production.- 32. Direct Action of Gonadotropin Releasing-Hormone and Visualization of Its Receptors on Porcine Ovaries.- 33. Role of Calcium in the Action of LHRH on Ovarian Progesterone Production.- 34. Modulation of Rat Inhibin mRNAs in Preovulatory and Atretic Follicles.- 35. Vasoactive Intestinal Peptide (VIP) Has an LH-Like Action on In Vitro Follicular Steroidogenesis But Not on Ovulation in the Cyclic Hamster.- 36. Mechanisms by Which Vasoactive Intestinal Peptide Regulate Baboon Granulosa Cell Steroidogenesis.- 37. Heparin-Binding Proteins in Purified Plasma Membranes of Bovine Granulosa Cells.- 38. Variations in the Interaction Between Follicular Glycosaminoglycans and Fibronectin Relative to the LH Surge in Cattle.- 39. Differences in the Ovulatory Ability Between the Right and Left Ovary Are Related to Ovarian Innervation.- 40. Differential Responses in the Component Cells of Graafian Follicles Perifused with Large and Small Doses of LH.- 41. The Rat Cholesterol Side-Chain Cleavage Cytochrome P450 (P450scc) Gene: cAMP-Dependent and -Independent Regulation in Ovarian Cells.- 42. Inhibitory Coupling Between Protein Kinase C and Cyclic AMP Generation in Swine Granulosa Cells.- 43. Luteinizing Hormone (LH)-Like Activity and Follicle-Stimulating Hormone (FSH) Are Sufficient for the Induction of Cystic Ovaries in Hypophysectomized Rats.- 44. Isolation of Steroidogenic Cell Subpopulations in the Follicular Theca of the Ovary in the Domestic Fowl.- 45. Evidence for an Endogenous Activator of Inositol Phospholipid Phospholipase C in Intact Rat Corpora Lutea.- 46. Estradiol-Induced Synthesis and Translation of Specific Proteins in the Corpus Luteum.- 47. Dual Activation of Adenylate Cyclase and Phospholipase C by Prostaglandins of the E and I Series in Bovine Luteal Cells.- 48. The Steroidogenic Response of Large and Small Luteal Cells to Dibutyryl cAMP and 25-OH-Cholesterol.- 49. Steroidal Regulation of Sterol Carrier Protein-2 and P450scc Expression in the Corpus Luteum.- 50. Regulation of HMG-CoA Reductase Gene Expression in the Corpus Luteum: Role of Estradiol.- 51. Pertussis Toxin Uncouples Enkephalin-Mediated Inhibition of Rabbit Luteal Adenylyl Cyclase.- 52. Attenuated In Vivo Progesterone Secretion by Ovine Corpora Lutea After Exposure to Luteinizing Hormone.- 53. Comparison of Gonadotropin- and Catecholamine-Induced Alterations of the Adenylyl Cyclase G-Proteins in Rabbit Corpora Lutea.- 54. Immunohistochemical and Morphological Observations of Macrophages in the Human Ovary.- 55. Phosphorylation of Sterol Carrier Protein 2 by Protein Kinase C.- 56. Histological Assessment of Ovarian Follicle Number in Mice as a Screen for Ovarian Toxicity.- 57. Ovarian Morphometric Changes Following Cyclophosphamide Treatment.- 58. Heparin, But Not N-Desulfated Heparin, Enhances Cumulus Expansion of Mouse and Cow Oocytes in Serum-Free Medium.- 59. A Fibronectin Receptor Competitive Blocker Inhibits GnRH Induced Meiosis in Follicle-Enclosed Oocytes.- Author Index.

Hirshfield, Anne N.

Hirshfield, Anne N.

[Book]

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