عنوان

Biological Basis of Oncologic Thermotherapy

3642749399

9783642749391

b551240

Biological Basis of Oncologic Thermotherapy

[Book]

edited by Michel Gautherie.

Berlin, Heidelberg

Springer Berlin Heidelberg

1990

(xi, 169 pages 116 illustrations)

Clinical thermology., Subseries thermotherapy.

1 Biological Basis of Thermotherapy (With Special Reference to Oncology) --;1.1 Introduction --;1.2 Methods of Hyperthermia Treatment --;1.3 Heat Transfer to Tissues and Temperature --;1.4 Biological Basis for the Action of Hyperthermia and of Combination with Ionizing Radiation --;1.5 Mechanisms of Action in Cell Killing --;1.6 Responses of Normal Tissues and Tumors --;1.7 Combination of Hyperthermia and Drugs --;1.8 Conclusions --;References --;2 Pathophysiological Mechanisms of Hyperthermia in Cancer Therapy --;2.1 Effects of Hyperthermia on Blood Flow Rates and Microcirculation in Normal and Neoplastic Tissues --;2.2 Microvascular Permeability in Tumors --;2.3 Temperature Distribution in Tumors --;2.4 Hyperthermia-Induced Changes in Nutrient and Oxygen Consumption Rates in Tumors --;2.5 Impact of Hyperthermia on the Cellular Microenvironment in Tumors --;2.6 Effect of Hyperthermia on Intracellular Ion Concentrations --;2.7 Conclusions --;References --;3 The Heat Shock Response: Events Before, During, and After Gene Activation --;3.1 Introduction --;3.2 Events Before Gene Activation --;3.3 Events During and Immediately After Gene Activation --;3.4 Late Events --;3.5 Conclusion --;References.

Studies on the effects of hyperthermia have aroused great interest in recent years. However, since it has been shown that radiation-induced cell killirtg can be remarkably enhanced by hyperthermia, many investigations have been performed with cells in vitro, tumors in situ, and normal tissues.

Medicine.

Oncology.

Radiotherapy.

edited by Michel Gautherie.

Michel Gautherie

[Book]

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