عنوان

Shock, sepsis, and organ failure

0387524959

3540524959

9780387524955

9783540524953

b550156

Shock, sepsis, and organ failure

[Book]

First Wiggers Bernard Conference. Günther Schlag ... (eds.).

Berlin u.a.

Springer

1990

x, 660 Seiten : Illustrationen, Diagramme

Literaturangaben.

Carl J. Wiggers.- Claude Bernard.- 1. What is Multi-Organ-Failure - Is it a Sequence of Organ Failures or a Systemic Disease?.- Clinical Manifestations and Sequences of Organ Failure.- Discussion.- The Specific Role of ARDS in the Development of Multiple Organ Failure.- Discussion.- Quantification of Organ Failure.- Discussion.- The Metabolic Basis of the Septic Multiple Organ Failure Syndrome: Abnormal Energetic Fuel Control, Pathophysiologic Proteolysis and Futile Cycling of Hepatically Synthesized Substrates.- Discussion.- Humoral and Cellular Activation in Blood Leading to Organ Failure.- Discussion.- Endothelium as the Interface Between Blood and Organ in the Evolution of Organ Failure.- Discussion.- Cellular Metabolic Responses in Endotoxemia, and a Hypothesis for the Mechanism of Hepatic Failure in Endotoxic Shock.- Discussion.- 2. Cellular Events in Trauma and Sepsis - Suppression Versus Activation or Both ?.- Posttraumatic Immune Suppression as Initiator of Organ Failure.- Humoral Factors in Immune Suppression After Injury.- Discussion.- Activation of Neutrophils and the Role of Eicosanoids in the Initiation of Organ Failure.- Discussion.- Role of Xanthine Oxidase-Derived Oxidants and Granulocytes in Ischemia/Reperfusion.- Discussion.- Role of Proteinases in the Pathophysiology of Organ Failure.- Discussion.- Activation of Cellular Membrane Receptors; Intracellular Messengers and Mediators of the Response to Injury.- Discussion.- 3. Mediators of Organ Failure - Are LPS or Sepsis Necessary ?.- Experimental Induction of Whole Body Inflammation Leads to ARDS, Multiple Organ Failure and Sepsis. The ZIGI-Model in Rats and Mice.- Discussion.- Endotoxin-Initiated Organ Failure Responses.- Discussion.- Through a Glass Darkly: The Gut in Multiple Organ Failure.- Discussion.- Changes in Mesenteric Blood Flow Affects Translocation in Sheep.- Discussion.- Antagonists of Platelet-Activating Factor as Potential Therapeutic Agents in Shock.- IL-1 and TNF: Mediators of LPS-Induced Neutrophil Emigration and Thrombosis.- Discussion.- 4. Conference Summary and Concluding Remarks.- Multiple Organ Failure as a Systemic Disease of Host-Defense Failure.- Final Discussion.

Organversagen.

Schock.

Sepsis.

First Wiggers Bernard Conference. Günther Schlag ... (eds.).

Günther Schlag

Wiggers Bernard Conference (1, 1989, Hof, Salzburg)

[Book]

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