I: General Aspects of Hepatic Failure --;Acute Liver Failure: History and Epidemiology --;Biochemistry of Liver Failure --;Mechanisms of Liver Cell Destruction --;Morphologic Aspects of Hepatic Regeneration --;Mechanisms of Regulation of Liver Regeneration --;Liver Regeneration: Molecular Mechanisms of Growth Control --;Animal Models of Hepatic Failure and Hepatic Encephalopathy --;Methods for the Assessment of Liver Function and Liver Regeneration --;Assessment of Liver Function in Donors by Use of the MEGX Test --;History of Artificial Liver Support --;II: Conservative Treatment --;Conservative Clinical Treatment of Acute Liver Failure --;Diagnosis and Therapy of Increased Intracranial Pressure and Brain Edema in Fulminant Hepatic Failure --;III: Hemoperfusion, Liver Perfusion, Dialysis, and Plasma Exchange --;Absorption Therapy in Acute Liver Failure: A Critical Resumé --;Selective Sorbent Hemoperfusion for Endotoxin --;Thermodynamic Criteria for the Removal of Certain Hepatic Insufficiency Markers from Protein-Containing Solutions --;Extracorporeal Hemoperfusion Over the Human and Baboon Liver --;Improved Methods of Extracorporeal Liver Perfusion for Temporary Replacement of Liver Function --;Pulmonary Microembolism Due to Plasma Exchange Replaced by Fresh Frozen Plasma --;Improved Plasma Exchange for the Treatment of Fulminant Hepatic Failure by Plasma Replacement into the Femoral Artery --;IV: Isolated and Immobilized Hepatocytes and Liver Tissue --;Cryopreserved Hepatocytes for Fluid Bed Reactors --;Artificial Cells for Artificial Liver Support --;Characteristics of Hepatocytes Immobilized Within Calcium Alginate and of a Bioreactor for Artificial Liver Support --;Immobilized Isolated Liver Cells on a Biomatrix --;Transplantation of Hepatocytes into the Spleen --;Problems and Controversies with Transplantation of Isolated Hepatocytes for Artificial Liver Support --;V: Enzymatic Liver Support and Lipophilic Hollow-Fiber Membranes --;Enzyme Preparation for Optimal Extracorporeal Enzymatic Detoxification --;Lipophilic Hollow Fiber Membranes for Enzymatic and Nonenzymatic Detoxification of Endogenous Lipophilic Toxins in Liver Disease --;Removal of Lipophilic Toxins from Blood by Matrix-Supported Lipid Materials --;Development of a Machine for Extracorporeal Removal of Lipophilic and Hydrophilic Toxins in Liver Failure --;VI: Surgical Support and Transplantation --;Can Resection of Cirrhotic Liver Stimulate Liver Regeneration? --;Intravasal Sclerotherapy of Esophagus and Fundic Varices as Therapy and Prophylaxis of Chronic Liver Failure --;Liver Transplantation Today: Indications and Results --;Hepatic Mitochondrial Redox Potential in Liver Transplantation and Artificial Liver Support --;Present Techniques and New Ideas for Liver Transplantation.
For these extreme forms of liver disease and for critical situations before and after liver surgery, artificial liver support is needed.