عنوان

Nuclear Imaging in Drug Discovery, Development, and Approval.

1468468103

9781468468106

b544175

Nuclear Imaging in Drug Discovery, Development, and Approval.

[Book]

Birkhauser

2012

pages

1. Nuclear Imaging in Drug Development-Introduction.- 2. Nuclear Medicine Physics, Instrumentation, and Data Processing in Pharmaceutical Research.- 3. Accelerators for Positron Emission Tomography.- 4. Chemistry of Tracers for Positron Emission Tomography.- 5. Single Photon, Gamma Emitting Radiotracers for Use in Imaging.- 6. The Design of Site-Directed Radiopharmaceuticals for Use in Drug Discovery.- 7. Applications of Autoradiography to Drug Discovery.- 8. Quantitative Whole Body Autoradiographic Microimaging for Pharmaceutical Research.- 9. Cerebral Metabolic Rates of 2-[18F]Fluoro-2-Deoxy-D-Glucose in the Presence of Ofloxacin A GABAA Receptor Antagonist.- 10. Positron Emission Tomography, Enzymes and Drug Research and Development.- 11. The Role of Positron Emission Tomography in Assessing and Monitoring Dopamine Active Drugs.- 12. Iodinated Dopamine D1 and D2 Receptor Imaging Agents for SPECT.- 13. Radiolabeled Atrial Natriuretic Peptide and Somatostatin for In Vivo Imaging of Receptors.- 14. Use of Radionuclides in Experimental Vascular Thrombosis.- 15. Application of Nuclear Imaging to Drug Delivery Evaluation and Development: A Review of Radiolabeled, Injectable, Colloidal Systems of Delivery.- 16. The Gastrointestinal Transit and Systemic Absorption of Diltiazem HCL from a Modified Release Dosage Form.- 17. The Potential Uses of Radiopharmaceuticals in the Pharmaceutical Industry.

[Book]

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