Fish oil and importance of its ingredients in human diet -- Transport, synthesis, and incorporation of n-3 and n-6 fatty acids in brain glycerophospholipids -- Release of n-3 and n-6 fatty acids from glycerophopholipids in brain -- Oxidation of arachidonic and docosahexaenoic acids and neurochemical effects of their metabolites on brain -- Roles of docasahexaenoic and eicosapentaenoic acids in brain -- Status of dicasahexaenoic acid levels in aging and consequences of docosahexaenoic acid deficiency in normal brain -- Status and potential therapeutic importance of n-3 fatty acids in neurodegenerative disease -- Status and potential therapeutic importance of n-3 fatty acids in acute metabolic trauma and neurotramatic disorders -- Status and potential therapeutic importance of n-3 fatty acids in neuropsychiatric disorders -- Status and potential therapeutic importance of n-3 fatty acids in other neural and non-neural diseases -- Perspective and directions for future development on the effects of fish oil constituents on brain