Neural stem cell models of development and disease -- Neural stem and progenitor cells: lineage and cell fate determination -- Stage-specific and cell fate markers -- Isolation of stem cells from multiple sites in the CNS -- Neural cells derived from embryonic stem cells -- On the origin of newly made neural cells in the adult organism: does transdifferentiation occur? -- Neural stem cell purification and clonal analysis -- Embryonic and neural stem cell lines -- Isolation, survival, proliferation, and differentiation of human neural stem cells -- Neuronal replacement by transplantation -- Derivation of myelin-forming cells for transplantation repair of the CNS -- Induction of adult cortical neurogenesis from neural precursors in situ -- Neural stem cells for cellular therapy in humans -- Genetic modification of neural stem/progenitor cells
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This book provides comprehensive, critical and insightful reviews by leading experts in this exciting field of research. It provides the latest data on neural stem cell properties and their therapeutic applications and will be particularly useful for students, basic scientists, and clinicians in the academic or industrial sectors who have an interest in understanding neural development and its application to repairing the nervous system
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