expansion of decoding rules enriches gene expression /
John F. Atkins, Raymond F. Gesteland, editors
New York :
Springer,
c2010
1 online resource (xix, 466 p.) :
ill
Nucleic acids and molecular biology,
24
Includes bibliographical references and index
Redefinition. Selenocysteine Biosynthesis, Selenoproteins, and Selenoproteomes. Reprogramming the Ribosome for Selenoprotein Expression: RNA Elements and Protein Factors -- Translation of UAG as Pyrrolysine -- Specification of Standard Amino Acids by Stop Codons -- Ribosome Skipping: Stop-Carry On or StopGo Translation -- Recoding Therapies for Genetic Diseases -- Frameshifting Redirection of Linear Readout. Pseudoknot-Dependent Programmed 1 Ribosomal Frameshifting: Structures, Mechanisms and Models -- Programmed 1 Ribosomal Frameshift in the Human Immunodeficiency Virus of Type 1 -- Ribosomal Frameshifting in Decoding Plant Viral RNAs -- Programmed Frameshifting in Budding Yeast -- Recoding in Bacteriophages -- Programmed Ribosomal -- 1 Frameshifting as a Tradition: The Bacterial Transposable Elements of the IS3 Family -- Autoregulatory Frameshifting in Antizyme Gene Expression Governs Polyamine Levels from Yeast to Mammals -- Sequences Promoting Recoding Are Singular Genomic Elements -- Mutants That Affect Recoding -- The E Site and Its Importance for Improving Accuracy and Preventing Frameshifts -- Discontiguity. Translational Bypassing Peptidyl-tRNA Re-pairing at Non-overlapping Sites -- trans -Translation -- Transcription Slippage. Transcript Slippage and Recoding -- Appendix. Computational Resources for Studying Recoding