عنوان

Cancer symptom science :

0521869013 (hardback)

9780521869010 (hardback)

dltt

Cancer symptom science :

[Book]

measurement, mechanisms, and management /

edited by Charles S. Cleeland, Michael J. Fisch, Adrian J. Dunn

New York :

Cambridge University Press,

2011

xvii, 356 p. :

ill. ;

26 cm

Cambridge medicine

Includes bibliographical references and index

Section I. Introduction: 1. Introduction to cancer symptom science / Charles S. Cleeland, Michael J. Fisch, and Adrian J. Dunn -- 2. Researching the mechanisms underlying the symptoms of patients with cancer / Adrian J. Dunn -- 3. Cytokines and sickness behavior: a model for cancer symptoms / Steven S. Zalcman, Randall T. Woodruff, Ruchika Mohla and Allan Siegal; Section II. Cancer Symptom Mechanisms and Models: Clinical and Basic Science: 4. The clinical science of cancer pain assessment and management / Victor T. Chang and Russell K. Portenoy -- 5. Pain: basic science -- 5a. Mechanisms of disease-related pain in cancer: insights from the study of bone tumors / Juan Miguel Jimenez Andrade and Patrick W. Mantyh -- 5b. The physiology of neuropathic pain / Haijun Zhang and Patrick M. Dougherty -- 6. Cognitive dysfunction: is chemobrain real? / Christina A. Meyers and Jeffrey S. Wefel -- 7. Cognitive impairment: basic science / Perry N. Fuchs, Jessica A. Boyette-Davis and Adrian J. Dunn -- 8. Depression in cancer: pathophysiology at the mind-body interface / Michael A. Burke, Charles L. Raison and Andrew H. Miller -- 9. Depressive illness: basic science -- 9a. Animal models of depressive illness and sickness behavior / Adrian J. Dunn -- 9b. From inflammation to sickness and depression: the cytokine connection / Robert Dantzer and Keith W. Kelly -- 10. Cancer-related fatigue: clinical science / Xin Shelley Wang -- 11. Developing translational animal models of cancer-related fatigue / Mary W. Meagher -- 12. Cancer anorexia/weight loss syndrome: clinical science / Nisha Lassi and Aminah Jatoi -- 13. Appetite loss/cachexia: basic science / Tristin D. Brisbois Clarkson, Wendy V. Wismer and Vickie E. Baracos -- 14. Sleep and its disorders: clinical science / Lianqi Liu and Sonia Ancoli-Israel -- 15. Sleep and its disorders: basic science / Mark R. Opp and Luca Imeri -- 16. Proteins and symptoms / Bang-Ning Lee and James M. Reuben -- 17. Genetic approaches to treating and preventing symptoms in patients with cancer / Quiling Shi and Charles S. Cleeland -- 18. Functional imaging of symptoms / T. Dorina Papageorgiou, Javier O. Valenzuela, and Edward F. Jackson -- 19. High-dose therapy and posttransplantation symptom burden: striking a balance / Sergio A. Giralt and Loretta A. Williams; Section III. Clinical Perspectives in Symptom Management and Research: 20. Promoting symptom research in cooperative groups / Lynne I. Wagner and David Cella -- 21. Practical aspects of symptom management in patients with cancer / Richard T. Lee and Michael J. Fisch -- 22. The economics of cancer-related symptome:valuing supportive-care interventions / Lesley-Ann Miller and Jane C. Weeks; Section IV. Symptom Measurement: 23. Symptom measurement by patient report / Charles S. Cleeland and Tito R. Mendoza -- 24 Longitudinal models for symptoms / Diane L. Fairclough -- 25. Bayesian adaptive design: a novel approach to test the effectiveness of symptom-reducing agents using patient-reported outcomes / Valen E. Johnson and Tito R. Mendoza; Section V. Government and Industry Perspectives: 26. Promoting cancer symptom science research / Ann O'Mara and Maria Sgambati -- 27. Developing symptom management drugs / Joanna M. Brell and Lori M. Minasian -- 28. Cancer-related symptoms: issues for consideration in drug and therapeutic biological product label claims in the United States / Jane A. Scott; Section VI. Conclusion: 29. Symptom research: looking ahead / Charles S. Cleeland, Michael J. Fisch and Adrian J. Dunn

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"Cancer Symptom Science is the first interdisciplinary compilation of research on the mechanisms underlying the expression of cancer-related symptoms. It presents innovations in clinical, animal and in vitro research, research methods in brain imaging, and statistical-descriptive approaches to understanding the mechanistic basis of symptom expression. This volume also provides perspectives from patients, government and industry. By collecting and synthesizing the developing threads of new approaches to understanding cancer-related symptoms, the book promotes a pioneering framework for merging behavioral and biological disciplines to clarify mechanisms of symptom evolution, incorporating new technologies, testing novel agents for symptom control, and improving patient functioning and quality of life both during and after cancer treatment. With an expert editorial team led by Charles S. Cleeland, an internationally-recognized leader in cancer pain assessment and treatment, this is essential reading for surgical, clinical and medical oncologists, academic researchers, and pharmaceutical companies developing new agents to control symptom expression"--Provided by publisher

Cancer-- Pathophysiology

Symptoms

Neoplasms-- physiopathology

Signs and Symptoms

Cleeland, Charles S

Dunn, Adrian J

Fisch, Michael J.,1964-

20110623105830.0

[Book]

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