Rob Phillips, Jane Kondev, Julie Theriot, Hernan G. Garcia ; illustrated by Nigel Orme
Second edition
xxx, 1,057 pages :
illustrations (chiefly color), maps ;
28 cm
Includes bibliographical references and index
Why : biology by the numbers -- What and where : construction plans for cells and organisms -- When : stopwatches at many scales -- Who : "bless the little beasties" -- Mechanical and chemical equilibrium in the living cell -- Entropy rules! -- Two-state systems : from ion channels to cooperative binding -- Random walks and the structure of macromolecules -- Electrostatics for salty solutions -- Beam theory : architecture for cells and skeletons -- Biological membranes : life in two dimensions -- The mathematics of water -- A statistical view of biological dynamics -- Life in crowded and disordered environments -- Rate equations and dynamics in the cell -- Dynamics of molecular motors -- Biological electricity and the Hodgkin-Huxley model -- Light and life -- Organization of biological networks -- Biological patterns : order in space and time -- Sequences, specificity, and evolution -- Whither physical biology?
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"Physical Biology of the Cell maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that unite a given set of biological phenomena. Herein lies the central premise: that the appropriate application of a few fundamental physical models can serve as the foundation of whole bodies of quantitative biological intuition, useful across a wide range of biological problems. The Second Edition features full-color illustrations throughout, two new chapters on the role of light in life and pattern formation, additional explorations of biological problems using computation, and significantly more end-of-chapter problems. This textbook is written for a first course in physical biology or biophysics for undergraduate or graduate students."--