1 computer disc (digital ; 4 3/4 in.) + 1 72 x 56 cm poster (folded to 18 x 28 cm)
Accompanying DVD-ROM includes: figures in PowerPoint and JPEG formats, supplementary sidebars, mini-lectures, movies, and media guide
Title on accompanying poster: Pathways in human cancer, revised edition
Includes bibliographical references and index
The biology and genetics of cells and organisms -- The nature of cancer -- Tumor viruses -- Cellular oncogenes -- Growth factors, receptors, and cancer -- Cytoplasmic signaling circuitry programs many of the traits of cancer -- Tumor suppressor genes -- pRb and control of the cell cycle clock -- p53 and apoptosis : master guardian and executioner -- Eternal life : cell immortalization and tumorigenesis -- Multi-step tumorigenesis -- Maintenance of genomic integrity and the development of cancer -- Dialogue replaces monologue : heterotypic interactions and the biology of angiogenesis -- Moving out : invasion and metastasis -- Crowd control : tumor immunology and immunotherapy -- The rational treatment of cancer