عنوان

Evaluation of meningitis and related factors in 12 to 18 months old children referring to Children’s Medical Center Tehran with fever and seizure from 2016 to 2021,بررسی مننژیت و عوامل مرتبط با آن در کودکان 12 تا 18 ماهه مراجعه کننده به مرکز طبی کودکان تهران با تب و تشنج از سال 1395 تا 1400

98091P

انگلیسی

Evaluation of meningitis and related factors in 12 to 18 months old children referring to Children’s Medical Center Tehran with fever and seizure from 2016 to 2021

بررسی مننژیت و عوامل مرتبط با آن در کودکان 12 تا 18 ماهه مراجعه کننده به مرکز طبی کودکان تهران با تب و تشنج از سال 1395 تا 1400

[Dissertation]

Bushra Fayaz

بشرا فیاض

Tehran University of Medical Sciences, Medicine school

2022

121p

Doctor of Medicine(MD)

INTRODUCTION: This is a retrospective cross-sectional study, performed with the aim of evaluating the meningitis and its related factors in 12 to 18 months old patients with fever and seizure. Children with meningitis often present with fever and seizure, it is necessary to evaluate the clinical factors associated with it.[9] For diagnosing the meningitis in children (12-18 months), LP is not an indication and only with the help of clinical manifestations can a physician diagnose it. [3] There is little information present regarding this issue.[9] Identifying the associated clinical factors could be major attempt to find the relationship between meningitis and fever and seizure in children. Our aim is to focus on the meningitis type as in septic or aseptic and their relationship with the clinical factors present in the patients with fever and seizure. We would like to signify the importance of vaccination 6 weeks prior seizures in these patients. This could help in better diagnosis related to the meningitis associated with fever and seizure in patients. METHODS: In this study, medical records from the archive of patients with fever and seizure who were admitted to CMC from 2016 to 2021 were used. The variables required for the study were obtained from the records. The data obtained was analysed by the SPSS software and the significance value of < 0.05 was considered. RESULTS: In this study 224 patients (12-18 months) with fever and seizure were studied. Meningitis was seen in 5.8% patients with fever and seizure (3 septic and 10 aseptic). 13 months old children had maximum frequency of meningitis. 6 male (46.15%) and 7 (53.8%) female patients had meningitis.A significant relationship was found between meningitis and age, focal seizure, drowsiness, positive blood culture and CRP levels. 13.7% patients of age 12 and 23.5% patients of age 13 were found to have meningitis. 10.3% patients with aseptic meningitis and 3.4% patient with septic meningitis were of age 12 months. 20.6% patients with aseptic meningitis and 2.9% patients with septic meningitis were of age 13 months. Out of 191 patients with generalized seizures, 5.8% had meningitis and out of 33 patients with focal seizures, 6% had meningitis. 76.92% patients with meningitis had drowsiness. 7.7% patients with meningitis (septic) had positive blood culture. 23% of patients with meningitis (1 septic; 2 aseptic) had high CRP levels. CONCLUSION: According to this study, meningitis was less frequent than expected in patients (12-18 months) with fever and seizure. Aseptic meningitis was more frequent than septic meningitis. The significant factors relating the patients with fever and seizure with meningitis were low age, drowsiness, focal seizures and CRP levels.

مقدمه: این مطالعه مقطعی گذشته نگر با هدف بررسی مننژیت و عوامل مرتبط با آن در بیماران تب و تشنج 12 تا 18 ماهه انجام شد. کودکان مبتلا به مننژیت اغلب با تشنج ناشی از تب تظاهر می‌کنند، بررسی عوامل بالینی مرتبط با آن ضروری است.]9[ برای تشخیص مننژیت در کودکان 12 تا 18 ماهگی، LP نشانه ای نیست و فقط با کمک تظاهرات بالینی پزشک می تواند آن را تشخیص دهد.]3[ اطلاعات کمی در مورد این موضوع وجود دارد.]9[ شناسایی عوامل بالینی مرتبط می‌تواند تلاش اصلی برای یافتن رابطه بین مننژیت و تب و تشنج در کودکان باشد. هدف ما تمرکز بر نوع مننژیت در سپتیک یا آسپتیک و ارتباط آن با عوامل بالینی موجود در بیماران تب و تشنج است. مایلیم اهمیت واکسیناسیون 6 هفته قبل از تب و تشنج را در این بیماران نشان دهیم. این می تواند به تشخیص بهتر مننژیت مرتبط با بیماران تب و تشنج کمک کندروش کار: در این مطالعه از سوابق پزشکی بیماران تب و تشنج که از سال 1395 تا 1400 در مرکز طبی کودکان بستری شده بودند استفاده شد. متغیرهای مورد نیاز برای مطالعه از سوابق به دست آمد. داده‌های به‌دست‌آمده با استفاده از نرم‌افزار SPSS مورد تجزیه و تحلیل قرار گرفت و مقدار معنی‌داری <0.05 در نظر گرفته شد.نتیجه گیری: بر اساس این مطالعه، مننژیت در بیماران )12 تا 18 ماهگی( با تب و تشنج کمتر شایع بود. مننژیت آسپتیک بیشتر از مننژیت سپتیک بود. عوامل مهم مرتبط با تب و تشنج بیماران مبتلا به مننژیت سن جوان، خواب آلودگی، تشنج کانونی و سطح CRP بود.

کودکان

Children

منژیت

Meningitis

تشخیص

Diagnosis

داده‌ه‍ا

Data

a04

a04

a06

a06

a09

a09

a11

a11

fever and seizure

, Author

, Author

Fayaz, Bushra

فیاض، بشرا

, Thesis advisor

, Thesis advisor

, Thesis advisor

, Consulting advisor

, Consulting advisor

Shervin Badv, Reza

Ghazizadeh Eslami, Golnaz

قاضی زاده اسلامی، گلناز

KHodabandeh

خدابنده

Tehran University of Medical Sciences, Medical school

ایران

20220831

390 pardis

p

TL

276903

a

Y