3D cell-based biosensors in drug discovery programs :microtissue engineering for high throughput screening
Three-dimensional cell-based biosensors in drug discovery programs
Boca Raton :
CRC Press,
c2010.
xvii, 386 p. :ill
مرجع به حساب نمي آيد
Includes bibliographical references and indexes.
"This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher.