/ by Masoud Rahman, Sophie Laurent, Nancy Tawil, L'Hocine Yahia, Morteza Mahmoudi
وضعیت نشر و پخش و غیره
محل نشرو پخش و غیره
Berlin, Heidelberg
نام ناشر، پخش کننده و غيره
: Springer Berlin Heidelberg :Imprint: Springer,
تاریخ نشرو بخش و غیره
, 2013.
مشخصات ظاهری
نام خاص و کميت اثر
X, 84 p. 24 illus., 20 illus. in color., online resource.
فروست
عنوان فروست
(Springer Series in Biophysics,0932-2353
مشخصه جلد
; 15)
یادداشتهای مربوط به نشر، بخش و غیره
متن يادداشت
Electronic
یادداشتهای مربوط به مندرجات
متن يادداشت
In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a 'biological identity' to their surfaces (referred to as a 'corona'), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called 'bio-nano interface, ' has been very rarely studied in detail to date, though the interest in this topic is rapidly growing. In this book, the importance of the physiochemical characteristics of nanoparticles for the properties of the protein corona is discussed in detail, followed by comprehensive descriptions of the methods for assessing the protein-nanoparticle interactions. The advantages and limitations of available corona evaluation methods (e.g. spectroscopy methods, mass spectrometry, nuclear magnetic resonance, electron microscopy, X-ray crystallography, and differential centrifugal sedimentation) are examined in detail, followed by a discussion of the possibilities for enhancing the current methods and a call for new techniques. Moreover, the advantages and disadvantages of protein-nanoparticle interaction phenomena are explored and discussed, with a focus on the biological impacts.
متن يادداشت
The Biological Significance of 'Nano' interactions -- Nanoparticle and Protein Corona -- Protein Corona: Applications and Challenges -- Analytical Methods for Corona Evaluations.?╗╣
فروست (داده ارتباطی)
عنوان
Springer Series in Biophysics,0932-2353
شماره جلد
15
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Life sciences
موضوع مستند نشده
Toxicology
موضوع مستند نشده
Biochemistry
موضوع مستند نشده
RNA-ligand interactions
موضوع مستند نشده
Nanotechnology
موضوع مستند نشده
Electronic books
رده بندی کنگره
شماره رده
E-BOOK
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )