عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
شماره کتابشناسی ملی
شماره
TLpq303854482
زبان اثر
زبان متن نوشتاري يا گفتاري و مانند آن
انگلیسی
عنوان و نام پديدآور
عنوان اصلي
Epizootic epitheliotropic disease of lake trout (Salvelinus namaycush):
نام عام مواد
[Thesis]
نام نخستين پديدآور
D. J. Medina
عنوان اصلي به قلم نويسنده ديگر
Etiology and pathogenesis
نام ساير پديدآوران
P. W. Chang
وضعیت نشر و پخش و غیره
نام ناشر، پخش کننده و غيره
University of Rhode Island
تاریخ نشرو بخش و غیره
1990
مشخصات ظاهری
نام خاص و کميت اثر
123
یادداشتهای مربوط به پایان نامه ها
جزئيات پايان نامه و نوع درجه آن
Ph.D.
کسي که مدرک را اعطا کرده
University of Rhode Island
امتياز متن
1990
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
A previously undescribed herpesvirus was isolated from juvenile lake trout (Salvelinus namaycush) undergoing epizootics of unknown etiology. The virus appears to be the etiological agent of the epizootics based on the following criteria: (1) it was isolated only from infected fish; (2) the disease could be induced with purified virus and 450 nm filtrates prepared from infected fish; (3) it produced clinical signs and lesions consistent with those observed during natural epizootics; (4) virus could be re-isolated from moribund fish experimentally infected with the virus and (5) the antibiotic oxytetracycline proved ineffective against it. The virus possesses all the characteristics of the family Herpesviridae. The virus is enveloped and measures 220-235 nm. The capsid has a diameter of 100-105 nm and contains 162 capsomeres, each of which has a hollow center. The virus is sensitive to chloroform, pH 3 and 11, and a temperature of 50C for 30 min. Fine structure studies of infected cells from skin of moribund fish also showed characteristics of herpesvirus. The infected cells contained numerous hexagonal virus particles, electron-dense fibrillar structures and donut shaped dense bodies in the nucleus. In the extracellular spaces, enveloped virus containing an eccentric nucleocapsid surrounded by an electron dense tegument were observed. The same type of structures have been described for other herpesviruses such as Herpes salmonis, channel catfish virus, Herpes simplex and cytomegalovirus. The herpesvirus caused mass mortality among juvenile lake trout. A study was conducted to determine the mechanism of death. Histopathogical studies of infected fish revealed extensive hypertrophy, hyperplasia, vacuolation and necrosis of the epithelium of the skin and oral mucosa. Some fish also showed hypertrophy, hyperplasia and fusion of gill epithelium with edema. Lesions of the kidney consisted of dilated capillaries of the glomeruli which filled Bowman's capsule. Measurements of the concentration of plasma sodium, potassium, chloride ions and plasma osmolality in 15 experimentally infected fish revealed a significant decrease. Plasma Na, K, and Cl concentrations, and plasma osmolality decreased 16%, 66%, 21% and 19% respectively. The total plasma protein concentration between infected and non-infected fish did not show any significant differences. It is hypothesized that the loss of integrity of the skin and oral mucosa, resulted in disruption of homeostasis which ultimately caused death.
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Animal diseases
موضوع مستند نشده
Animal diseases
موضوع مستند نشده
Aquaculture
موضوع مستند نشده
Biological sciences
موضوع مستند نشده
Fish production
موضوع مستند نشده
Zoology
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )
مستند نام اشخاص تاييد نشده
D. J. Medina
مستند نام اشخاص تاييد نشده
P. W. Chang
دسترسی و محل الکترونیکی
نام الکترونيکي
مطالعه متن کتاب وضعیت انتشار
فرمت انتشار
p
اطلاعات رکورد کتابشناسی
نوع ماده
[Thesis]
کد کاربرگه
276903
اطلاعات دسترسی رکورد
سطح دسترسي
a
تكميل شده
Y
