عنوان

Synthesis of Novel Thiazole and Pyrazole Derivatives as Antimicrobial and Anticancer Agents

شماره

TLpq2447299030

زبان متن نوشتاري يا گفتاري و مانند آن

انگلیسی

عنوان اصلي

Synthesis of Novel Thiazole and Pyrazole Derivatives as Antimicrobial and Anticancer Agents

نام عام مواد

[Thesis]

نام نخستين پديدآور

Khan, Md Mahbub Kabir

نام ساير پديدآوران

Alam, Mohammad A.

نام ناشر، پخش کننده و غيره

Arkansas State University

تاریخ نشرو بخش و غیره

2020

نام خاص و کميت اثر

204

جزئيات پايان نامه و نوع درجه آن

M.S.

کسي که مدرک را اعطا کرده

Arkansas State University

امتياز متن

2020

متن يادداشت

This thesis contains two chapters. In chapter one, I report the synthesis of new pyrazole derivatives from dicarboxylic acid containing phenyl-derived, monotrifluoromethyl phenyl-derived, and acetovanillone-derived pyrazole aldehydes using Hantzsch ester. All of our pyrazole compounds have been synthesized efficiently using Hantzsch ester without any catalyst. Most of our pyrazole and thiazole compounds have been effectively recrystallized with acetonitrile and methanol respectively. We have synthesized 99 different pyrazole, 17 fused-thiazole ethisterone, and D-(-) norgestrel derivatives in good yield. In the present research, it has been shown possible to synthesize novel pyrazoles and thiazoles by using readily available starting materials and benign reaction conditions. Most of our compounds showed promising activity against several Gram-positive bacterial strains. All of these pyrazole and thiazole molecules have been identified by 1H NMR and 13C NMR spectroscopy and chemical structures have been confirmed by High Resolution Mass Spectrometry (HRMS).

موضوع مستند نشده

Chemistry

موضوع مستند نشده

Organic chemistry

مستند نام اشخاص تاييد نشده

Alam, Mohammad A.

مستند نام اشخاص تاييد نشده

Khan, Md Mahbub Kabir

نام الکترونيکي

فرمت انتشار

p

نوع ماده

[Thesis]

کد کاربرگه

276903

سطح دسترسي

a

تكميل شده

Y