عنوان

New antibiotic targets /

شابک

1597452467

شابک

9781597452465

شابک اشتباه

1588299155

شابک اشتباه

9781588299154

شماره

b796587

عنوان اصلي

New antibiotic targets /

نام عام مواد

[Book]

نام نخستين پديدآور

edited by W. Scott Champney.

محل نشرو پخش و غیره

Totowa, N.J. :

نام ناشر، پخش کننده و غيره

Humana Press,

تاریخ نشرو بخش و غیره

©2008.

نام خاص و کميت اثر

1 online resource (xi, 274 pages) :

ساير جزييات

illustrations

عنوان فروست

Methods in molecular medicine ;

مشخصه جلد

142

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

Biocomputational strategies for microbial drug target identification / K.R. Sakharkar, M.K. Sakharkar and V.T. Chow -- Methods to assay inhibitors of DNA gyrase and topoisomerase iv activities / L.M. Fisher and X.S. Pan -- A method to assay inhibitors of DNA polymerase iiic activity / M.M. Butler and G.E. Wright -- Methods to identify and characterize inhibitors of bacterial RNA polymerase / A.S. Lynch and Q. Du -- Methods to assay inhibitors of trna synthetase activity / D. Beyer, H.P. Kroll and H. Brotz-Oesterhelt -- Three methods to assay inhibitors of ribosomal subunit assembly / W.S. Champney -- Inhibition of chaperone-dependent bacterial ribosome biogenesis / A. Al Refaii and J.H. Alix -- Assays for the identification of inhibitors targeting specific translational steps / L. Brandi, J. Dresios and C.O. Gualerzi -- Spark: A new peptidyl transferase activity assay / A.S. Mankin and N. Polacek -- High-throughput screening of peptide deformylase inhibitors / K.T. Nguyen and D. Pei -- A method to assay penicillin-binding proteins / M.J. Pucci and T.J. Dougherty -- A method to assay inhibitors of lipopolysaccharide synthesis / M. Hernick and C.A. Fierke -- Methods for assessing the structure and function of cationic antimicrobial peptides / M. Pate and J. Blazyk -- Flow cytometry of bacterial membrane potential and permeability / H.M. Shapiro -- Bacterial efflux pump inhibitors / B.J. Kamicker [and others] -- Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase iii (mtfabh) assay: Principles and method / S. Sachdeva and K.A. Reynolds -- Screening for compounds that affect the interaction between bacterial two-component signal transduction response regulator protein and cognate promoter DNA / M.G. Erickson, A.T. Ulijasz and B. Weisblum -- The activity of rrna resistance methyltransferases assessed by maldi mass spectrometry / S. Douthwaite, R.L. Jensen and F. Kirpekar -- Assays for beta-lactamase activity and inhibition / T. Viswanatha [and others] -- Studies of enzymes that cause resistance to aminoglycosides antibiotics / E.H. Serpersu, C. Ozen and E. Wright.

بدون عنوان

0

متن يادداشت

A crisis is developing in the treatment of infectious diseases, with microorganisms frequently showing resistance to currently prescribed antibiotics. Fewer and fewer antimicrobial agents are now available to treat these infections. In "New Antibiotic Targets, " W. Scott Champney examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. By testing new antimicrobial agents and modified existing drugs, the most vulnerable cell processes, such as cell wall and membrane synthesis, DNA replication, RNA transcription and protein synthesis, can be better exploited. This in-depth volume, however, delves even deeper by identifying additional novel cellular targets for these new therapies. With detailed methods and protocols for the identification and assay of these targets, "New Antibiotic Targets" provides laboratory investigators with the vital tools they need to test the antimicrobial potential of products and to curb the rise of so many infectious diseases.

عنوان

New antibiotic targets.

شماره استاندارد بين المللي کتاب و موسيقي

9781588299154

موضوع مستند نشده

Anti-infective agents-- Testing.

موضوع مستند نشده

Drug resistance in microorganisms.

موضوع مستند نشده

Drug targeting.

موضوع مستند نشده

Anti-Infective Agents.

موضوع مستند نشده

Drug Delivery Systems-- methods.

موضوع مستند نشده

Drug Resistance, Microbial.

موضوع مستند نشده

Anti-infective agents-- Testing.

موضوع مستند نشده

Drug resistance in microorganisms.

موضوع مستند نشده

Drug targeting.

موضوع مستند نشده

MED022090

موضوع مستند نشده

MJCJ

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

شماره رده

نشانه اثر

نشانه اثر

مستند نام اشخاص تاييد نشده

Champney, W. Scott.

تاريخ عمليات

20201207092532.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y