عنوان

MTOR pathway and mTOR inhibitors in cancer therapy /

شابک

1603272704

شابک

1603272712

شابک

9781603272704

شابک

9781603272711

شماره

b779464

عنوان اصلي

MTOR pathway and mTOR inhibitors in cancer therapy /

نام عام مواد

[Book]

نام نخستين پديدآور

Vitaly A. Polunovsky, Peter J. Houghton, editors.

محل نشرو پخش و غیره

New York :

نام ناشر، پخش کننده و غيره

Humana Press,

تاریخ نشرو بخش و غیره

©2010.

نام خاص و کميت اثر

1 online resource (xii, 301 pages)

عنوان فروست

Cancer drug discovery and development

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

mTORC1: a signalling integration node involved in cell growth -- The regulation of the IGF-1/mTOR pathway by the p53 tumor suppressor gene functions -- mTOR signaling in angiogenesis -- mTORC1 signaling and hypoxia -- mTOR signaling in glioblastoma: lessions learned from bench to bedside -- mTOR and cancer therapy: general principles -- mTOR and cancer therapy: clinical development and novel prospects -- Drug combinations as a therapeutic approach for mTORC1 inhibitors in human cancer -- Downstream targets of mTORC1 -- Downstream of mTOR: translational and control of cancer -- Genome-wide analysis of translational control -- Translational control of cancer: implications for targeted therapy -- Downstream from mTOR: therapeutic approaches to targeting the eIF4F translation initiation complex.

بدون عنوان

0

متن يادداشت

MTOR Pathway and mTOR Inhibitors in Cancer Therapy provides an up-to-date survey of the rapidly advancing field of cancer therapy. Our understanding of the mechanisms involved in cancer genesis and progression underwent unprecedented expansion during the last decade, opening a new era of cancer treatment - targeted therapy. The surge in this area results in no small part from studies conducted jointly by basic health scientists and clinical investigators. It is our hope that this book will help foster even further collaboration between investigators in these two disciplines. In this work, experts in TOR signaling have contributed in two thematic areas: mTOR Signaling and Cancer Therapy (chapters 1 - 8) and Therapeutic Targeting Downstream of mTOR (chapter 9 - 13). All chapters of mTOR Pathway and mTOR Inhibitors in Cancer Therapy are completely new or have been extensively updated by their authors; and we are indebted to all authors who have exemplified the links between these 2 thematic areas.

منبع سفارش / آدرس اشتراک

Springer

شماره انبار

978-1-60327-270-4

عنوان

MTOR pathway and mTOR inhibitors in cancer therapy.

شماره استاندارد بين المللي کتاب و موسيقي

9781603272704

موضوع مستند نشده

Cancer-- Treatment.

موضوع مستند نشده

Antineoplastic Agents-- therapeutic use.

موضوع مستند نشده

Enzyme Inhibitors-- therapeutic use.

موضوع مستند نشده

Neoplasms-- drug therapy.

موضوع مستند نشده

Protein-Serine-Threonine Kinases-- therapeutic use.

موضوع مستند نشده

Cancer-- Treatment.

موضوع مستند نشده

HEALTH & FITNESS-- Diseases-- Cancer.

موضوع مستند نشده

Médecine.

موضوع مستند نشده

MEDICAL-- Oncology.

موضوع مستند نشده

HEA-- 039030

موضوع مستند نشده

MED-- 062000

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

شماره رده

مستند نام اشخاص تاييد نشده

Houghton, Peter J.

مستند نام اشخاص تاييد نشده

Polunovskiĭ, V. A., (Vitaliĭ Aleksandrovich)

تاريخ عمليات

20201206183357.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y