عنوان

Approaches to the conformational analysis of biopharmaceuticals /

شابک

1439807809

شابک

9781439807804

شماره

b713362

عنوان اصلي

Approaches to the conformational analysis of biopharmaceuticals /

نام عام مواد

[Book]

نام نخستين پديدآور

Roger L. Lundblad.

محل نشرو پخش و غیره

Boca Raton :

نام ناشر، پخش کننده و غيره

CRC Press,

تاریخ نشرو بخش و غیره

©2010.

نام خاص و کميت اثر

xiii, 354 pages :

ساير جزييات

illustrations ;

ابعاد

25 cm.

عنوان فروست

Protein science series

متن يادداشت

Includes bibliographical references and index.

متن يادداشت

Introduction to biopharmaceutical conformational analysis : issues and methods -- Comparability of biotechnological/biological products and biological generics -- Application of native electrophoresis for the study of protein conformation -- Affinity chromatography including hydrophobic interaction chromatography in the study of biopolymer conformation -- Size-exclusion chromatography and bimolecular conformation -- Use of analytical ultracentrifugation to study biomolecular conformation -- Use of differential scanning calorimetry to measure conformational change in proteins and other biomacromolecules -- Light scattering and biomacromolecular conformation -- Use of luminescence to measure conformational change in biopharmaceuticals with emphasis on protein and protein drug products -- Near-infrared spectroscopy and macromolecular conformation -- Use of mid-infrared and Fourier transform infrared spectroscopy to study conformation of biomacromolecules -- Use of Raman spectroscopy to evaluate biopharmaceutical conformation -- The use of UV-VIS spectrophotometry for the characterization of biopharmaceutical products -- Use of optical rotatory dispersion and circular dichroism to study therapeutic biomacromolecule conformation -- Use of nuclear magnetic resonance for the characterization of biotherapeutic products -- Use of chemical probes for the study of protein conformation -- Use of hydrogen exchange in the study of biopharmaceutical conformation -- Use of chemical modification for the conformational analysis of biopharmaceuticals -- Use of immunology to characterize biopharmaceutical conformation -- Use of limited proteolysis to study the conformation of proteins of biotechnological interest -- Other technologies for the characterization of conformational change in biopharmaceuticals -- Development of an experimental approach for the study of the conformation of a biological therapeutic product.

بدون عنوان

0

موضوع مستند نشده

Pharmaceutical biotechnology.

موضوع مستند نشده

Protein drugs-- Conformation.

موضوع مستند نشده

Biopharmaceutics-- methods.

موضوع مستند نشده

Protein Conformation.

موضوع مستند نشده

Proteins-- analysis.

موضوع مستند نشده

Pharmaceutical biotechnology.

شماره

ويراست

شماره رده

نشانه اثر

شماره رده

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

Lundblad, Roger L.

تاريخ عمليات

20201208034540.0

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y