Cell-based therapy for degenerative retinal disease /
نام عام مواد
[Book]
نام نخستين پديدآور
Marco A. Zarbin, Mandeep S. Singh, Ricardo P. Casaroli-Marano, editors.
وضعیت نشر و پخش و غیره
محل نشرو پخش و غیره
Cham, Switzerland :
نام ناشر، پخش کننده و غيره
Humana Press,
تاریخ نشرو بخش و غیره
2019.
مشخصات ظاهری
نام خاص و کميت اثر
1 online resource (xi, 280 pages) :
ساير جزييات
illustrations (some color)
فروست
عنوان فروست
Stem cell biology and regenerative medicine,
شاپا ي ISSN فروست
2196-8985
يادداشت کلی
متن يادداشت
Includes index.
یادداشتهای مربوط به مندرجات
متن يادداشت
Intro; Preface; Contents; Contributors; Chapter 1: Advantages of the Eye as a Target Organ for Cell-Based Therapy in the Central Nervous System; Introduction; Advantages of the Eye as a Target Organ; Anatomy and Physiology; Surgical Access; Immune Privilege; Antigen Load; High-Resolution Noninvasive Imaging Technology; Functional Assessment of the Transplant; Conclusions; References; Chapter 2: Proof of Principle: Preclinical Data on Retinal Cell Transplantation; Introduction; Photoreceptor Rescue Therapy; RPE Transplantation; Neural and Retinal Progenitor Cell Transplantation
متن يادداشت
Age-Related Macular DegenerationClinical Characteristics; Genetic Association and Pathophysiology; Ophthalmoscopic Features; Imaging and Other Useful Tests; Fluorescein Angiography; Optical Coherence Tomography; Fundus Autofluorescence; Electrophysiological Testing; Differential Diagnosis; ABCA4 (Stargardt) Dystrophy; Clinical Characteristics; Genetic Association and Pathophysiology; Ophthalmoscopic Features; Imaging and Other Useful Tests; Fundus Autofluorescence; Fluorescein Angiography; Optical Coherence Tomography; Electrophysiological Testing; Differential Diagnosis; Best Disease
متن يادداشت
Bone Marrow Cell TransplantationUmbilical Tissue-Derived Cell Transplantation; Photoreceptor Replacement Therapy; Neuroretinal Sheet Transplantation; Photoreceptor Cell Transplantation; Retinal Cellular Materials Transfer; Conclusion; References; Chapter 3: Clinical and Pathological Features of Selected Human Retinal Degenerative Diseases; Introduction; Generalized Retinal Degenerations; Retinitis Pigmentosa; Clinical Characteristics; Genetic Associations and Pathophysiology; Ophthalmoscopic Features; Imaging and Other Useful Tests; Perimetry and Electrophysiological Testing
Fundus AutofluorescenceFluorescein Angiography; Optical Coherence Tomography (OCT); Differential Diagnosis; Leber Congenital Amaurosis; Clinical Characteristics; Genetic Association and Pathophysiology; Ophthalmoscopic Features; Imaging and Other Useful Tests; Fundus Autofluorescence, Fluorescein Angiography, and OCT; Psychophysical and Electrophysiological Testing; Differential Diagnosis; Choroideremia; Clinical Characteristics; Genetic Association and Pathophysiology; Ophthalmoscopic Features; Imaging and Other Useful Tests; Differential Diagnosis; Central Degenerations
بدون عنوان
0
بدون عنوان
8
بدون عنوان
8
بدون عنوان
8
بدون عنوان
8
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
This book discusses why specific diseases are being targeted for cell-based retinal therapy, what evidence exists that justifies optimism for this approach, and what challenges must be managed in order to bring this technology from the laboratory into routine clinical practice. There are a number of unanswered questions (e.g., surgical approach to cell delivery, management of immune response, optimum cell type to transplant) that very likely are not going to be answered until human trials are undertaken, but there is a certain amount of "de-risking" that can be done with preclinical experimentation. This book is essential reading for scientists, clinicians, and advanced students in stem cell research, cell biology, and ophthalmology.
یادداشتهای مربوط به سفارشات
منبع سفارش / آدرس اشتراک
Springer Nature
شماره انبار
com.springer.onix.9783030052225
ویراست دیگر از اثر در قالب دیگر رسانه
عنوان
Cell-based therapy for degenerative retinal disease.