عنوان

Surface enhanced raman spectroscopy for biophysical applications :

شابک

3030035565

شابک

9783030035563

شابک اشتباه

3030035557

شابک اشتباه

9783030035556

عنوان اصلي

Surface enhanced raman spectroscopy for biophysical applications :

نام عام مواد

[Book]

ساير اطلاعات عنواني

using plasmonic nanoparticle assemblies /

نام نخستين پديدآور

Claudia Fasolato.

محل نشرو پخش و غیره

Cham, Switzerland :

نام ناشر، پخش کننده و غيره

Springer,

تاریخ نشرو بخش و غیره

2018.

نام خاص و کميت اثر

1 online resource (xviii, 155 pages) :

ساير جزييات

illustrations (some color)

عنوان فروست

Springer theses,

شاپا ي ISSN فروست

2190-5053

متن يادداشت

"Doctoral thesis accepted by the Sapienze University of Rome, Rome, Italy."

متن يادداشت

Intro; Supervisor's Foreword; Abstract; Parts of this thesis have been published in the following articles; Acknowledgements; Contents; 1 Introduction; References; 2 Traditional Raman and SERS: Fundamentals and State of the Art; 2.1 Optical Vibrational Spectroscopy of Molecules; 2.1.1 Theory of Raman Scattering; 2.2 Surface Enhanced Raman Scattering; 2.2.1 Electromagnetic Mechanism; 2.2.2 Chemical Mechanism; 2.3 Current Trends in Surface Enhanced Raman Scattering; 2.3.1 Nanoparticle-Based SERS Substrates; 2.3.2 SERS Applications in Nanomedicine

متن يادداشت

2.3.3 Non Metallic Substrates: SERS from Semiconductor NanostructuresReferences; 3 Investigation on Nanoparticles and Their Molecular Functionalization; 3.1 Model Functionalization with 4ATP Linker; 3.1.1 Preparation and Control Characterization; 3.1.2 SERS Versus Raman Spectrum; 3.2 Further Conjugation: Folate and Antifolates; 3.2.1 Nanovector Functionalization: The Case of Folate; 3.2.2 SERS Signature of Folate/Antifolate Nanovectors; 3.3 Experimental Details; References; 4 Nanoparticle-Based SERS Substrates for Molecular Sensing Applications

متن يادداشت

4.1 Self-assembled Mesoscopic Silver Nanoparticle Clusters4.1.1 Coupled AFM and Raman Analysis; 4.1.2 Dimensional Scale Effect on SERS Efficiency; 4.2 FDTD Simulation: Theoretical Predictions; 4.2.1 The FDTD Software; 4.2.2 Results on Silver and Gold Np Multilayers; 4.3 Electron Beam Lithography Driven Self-assembly; 4.3.1 Nanoparticle Cluster Array Preparation; 4.3.2 Analysis of the Patterned Arrays; 4.3.3 Analysis of the Ordered Nanoparticle Cluster Arrays; 4.3.4 SERS Reproducibility; References; 5 SERS-Active Nanovectors for Single-Cell Cancer Screening and Theranostics

متن يادداشت

5.1 Early Cancer Diagnostics and Theranostics5.2 Folate-Based SERS Diagnostics; 5.2.1 Idea of the Experiment; 5.2.2 Cell Treatment and Viability Tests; 5.2.3 Raman and SERS Imaging on Treated Cells; 5.2.4 SEM Imaging on Treated Cells; 5.2.5 SERS Screening and Results; 5.3 From Selectivity to Theranostics: Antifolate Nanovectors; 5.3.1 Preliminary Cytotoxicity Results; 5.3.2 Enhanced Toxicity of Nanostructured Drugs; References; 6 Conclusions; A SERS Application in Cultural Heritage; A.1 HPTLC-SERS Investigation of Madder Lake Ammonia Extract; A.1.1 HPTLC-SERS Analytical Method

متن يادداشت

A.1.2 Experimental ResultsA. 2 A Multianalytical Study Unravels Purple Dyeing Processes: The Case of a Historical Dress from the 19th Century; A.2.1 Introduction; A.2.2 Sicilian Noblewoman Dress: Microscopy, Sampling, Experimental Details; A.2.3 Results and Discussion; A.2.4 Conclusions; Curriculum Vitae

بدون عنوان

0

بدون عنوان

8

بدون عنوان

8

بدون عنوان

8

بدون عنوان

8

متن يادداشت

The book explores the phenomenon of surface-enhanced Raman scattering (SERS), the huge amplification of Raman signal from molecules in the proximity of a metallic nanostructured surface, allowing readers to gain an in-depth understanding of the mechanisms affecting the spectroscopic response of SERS-active systems for effective applications. SERS spectroscopy is an ultrasensitive analytical technique with great potential for applications in the field of biophysics and nanomedicine. As examples, the author presents the design of nanocolloid-based SERS-active substrates for molecular sensing and of a folate-based SERS-active nanosensor capable of selectively interacting with cancer cells, enabling cancer diagnostics and therapy at the single-cell level. The author also suggests novel paths for the systematization of the SERS nanosystem design and experimental protocols to maximize sensitivity and reproducibility, which is essential when real-world biomedical applications are the goal of the study. With a combined approach, both fundamental and applied, and a detailed analysis of the state of the art, this book provides a valuable overview both for students new to SERS spectroscopy and for experts in the field.

منبع سفارش / آدرس اشتراک

Springer Nature

شماره انبار

com.springer.onix.9783030035563

شماره استاندارد بين المللي کتاب و موسيقي

9783030035556

شماره استاندارد بين المللي کتاب و موسيقي

9783030035570

موضوع مستند نشده

Raman effect, Surface enhanced.

موضوع مستند نشده

Raman spectroscopy.

موضوع مستند نشده

Raman effect, Surface enhanced.

موضوع مستند نشده

Raman spectroscopy.

موضوع مستند نشده

PDN

موضوع مستند نشده

PNFS

موضوع مستند نشده

PNFS

موضوع مستند نشده

SCI078000

شماره

ويراست

شماره رده

مستند نام اشخاص تاييد نشده

Fasolato, Claudia

تاريخ عمليات

20200823075542.0

قواعد فهرست نويسي ( بخش توصيفي )

pn

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y