عنوان

Coronary Circulation in Physiological and Pathophysiological States

شابک

4431681086

شابک

9784431681083

شماره

b590910

عنوان اصلي

Coronary Circulation in Physiological and Pathophysiological States

نام عام مواد

[Book]

نام نخستين پديدآور

edited by Motoomi Nakamura, Paul M. Vanhoutte.

محل نشرو پخش و غیره

Tokyo Springer Japan

تاریخ نشرو بخش و غیره

1991

نام خاص و کميت اثر

(XIII, 160 p)

متن يادداشت

MOTOOMI NAKAMURA As we approach the 21st century, ischemic heart disease is the major cause of death in most of the developed nations of the world. Since the 1970s, much effort and expense have led to designs of coronary thrombolytic therapy, percutaneous coronary angioplasty (PTCA), coronary artery bypass grafting, heart transplantation, automatic defibrillators, as well as to the formation of beta blockers and com­ pounds which block the calcium channel. Socio-educational programs directed at exercise, diet, instruction in the risk factors of smoking, hyperlipidemia and hypertension have contributed to the decrease in the rate of morbidity and mortality of patients with ischemic heart disease. However, the first clinical event of ischemic heart disease, the so-called "heart attack" and sudden cardiac death continues to present problems, as the mechanisms involved in these events are poorly understood. It has long been thought that ischemic heart disease is the sequence of an organic fixed atherosclerotic obstruction of the epicardial coronary arteries and the role of coronary vasomotion has been given much less attention. Recent clinical and laboratory animal studies revealed that increased tonus and spasm of the large epicardial coronary arteries are the cause of various stages of ischemic heart disease. The role of coronary vasospasm in the development of un­ stable angina, sudden cardiac death and acute myocardial infarction remains open to debate. Pharmacophysiological studies showed that the epicardial large coronary artery contributes only 5% to regulation of normal coronary flow.

موضوع مستند نشده

Cardiology.

موضوع مستند نشده

Human Physiology.

موضوع مستند نشده

Pathology.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

edited by Motoomi Nakamura, Paul M. Vanhoutte.

مستند نام اشخاص تاييد نشده

Motoomi Nakamura

مستند نام اشخاص تاييد نشده

Paul M Vanhoutte

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y