عنوان

Transgenic Animals as Model Systems for Human Diseases

شابک

3662029251

شابک

9783662029251

شماره

b579254

عنوان اصلي

Transgenic Animals as Model Systems for Human Diseases

نام عام مواد

[Book]

نام نخستين پديدآور

edited by Erwin F. Wagner, Franz Theuring.

محل نشرو پخش و غیره

Berlin, Heidelberg

نام ناشر، پخش کننده و غيره

Springer Berlin Heidelberg

تاریخ نشرو بخش و غیره

1993

نام خاص و کميت اثر

(xii, 151 pages)

عنوان فروست

Schering Foundation workshop, 6.

متن يادداشت

1 The Human Renin-Angiotensin System in Transgenic Rats --; New Tools for Antihypertensive Therapy --; 2 Probing the Genetics of Atherosclerosis in Transgenic Mice --; 3 The PrP-less Mouse: A Tool for Prion Research --; 4 The Carboxyterminal Fragment of the Alzheimer Amyloid Protein Precursor Causes Neurodegeneration In Vivo --; 5 Transgenic Models of Chronic Arthritis and of Systemic Tumour Necrosis Factor-Mediated Disease in Mice Expressing Human Tumour Necrosis Factor --; 6 Mammary Neoplasia in Mouse Mammary Tumor Virus-Transforming Growth Factor? Transgenic Mice --; 7 Exploring the Pathogenic Potential of c-fos, Polyoma Middle T and Human Foamy Virus in Transgenic Mice --; 8 Transgenic Animals as Bioreactors for Therapeutic and Nutritional Proteins --; 9 Targeted Inactivation of the Muscle Regulatory Genes Myf-5 and MyoD: Effect on Muscle and Skeletal Development.

متن يادداشت

Some of the current concepts used in transgenic research, an increasingly important tool to study the regulation and function of genes, are illustrated in this book. With these techniques, animal models can be used to study human diseases; this opens up new possibilities in both applied and basic research. Specifically, the ability to introduce genes into the germline of mice and the successful expression of the inserted gene within an organism provide new insights and opportunities for biomedical research. The discussion here shows how a detailed analysis of the underlying molecular mechanisms will provide new insights into the genetic origin of certain diseases and will lead to a better understanding of normal and abnormal physiological processes.

موضوع مستند نشده

Biomedical engineering.

موضوع مستند نشده

Engineering.

موضوع مستند نشده

Microbiology.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

edited by Erwin F. Wagner, Franz Theuring.

مستند نام اشخاص تاييد نشده

Erwin F Wagner

مستند نام اشخاص تاييد نشده

F Theuring

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y