I. Volume of Distribution --; II. Compartments --; 1. Protein Binding --; 2. Gastrointestinal Reabsorption --; III. Elimination --; 1. Equation for Elimination --; IV. Steady State --; 1. Conditions for a Steady State --; 2. Artificial Steady State --; Continous Infusion --; V. Multicompartment Systems --; 1. The Model --; 2. Dost's Principle of Corresponding Areas --; 3. Dost's Rule of Corresponding Fractional Areas --; 4. General Consideration of Multicompartment Models --; VI. Pharmacokinetics and Treatment --; 1. Repeated Administration of a Drug --; VII. Pharmacokinetics of Gastrointestinal Absorption --; 1. Gastrointestinal Absorption and the Bateman Function --; 2. Reconstruction of the Invasion Curves --; 3. Use of the Invasion Curves --; 4. Calculation of Dose-Proportional Absorption --; 5. Variants of the Invasion Process in Gastrointestinal Absorption --; 6. Conclusions --; 7. Appendix: Some Formulae and Their Derivation --; VIII. Interaction --; 1 Elimination --; 2. Volume of Distribution --; 3. Conclusions --; IX. Use of Analogue Computers in Pharmacokinetics --; 1. Principle of the Analogue Computer --; 2. Programming the Analogue Computer --; 3. Use --; X. Practical Application of Pharmacokinetic Procedures --; 1. Methods of Measurement --; 2. Assessment of the Results of Animal Experiments --; 3. Derivation of Pharmacokinetic Parameters and Constants --; 4. Mathematical Basis of Programming --; 5. Examples of Calculation --; Further Reading.
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
This is a little book with no great pretensions. The authors do not claim it to be world-startling nor Nobel- or Pulitzer-prize-winning. It is a valuable primer for pharmacokinetics for those desiring a proper initiation into previously assumed mysteries. It is fully intended as an introduction to the basic concept of pharmacokinetics and will be welcomed by all who wish to apply its principles to their own disciplines, whether in life sciences or medicine, without being confused by excess mathematics. It is edited by two well-known German scientists who are primarily practicing pediatricians.
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Medicine.
موضوع مستند نشده
Pharmacy.
موضوع مستند نشده
Toxicology.
رده بندی کنگره
شماره رده
RM301
.
5
نشانه اثر
B944
1979
نام شخص به منزله سر شناسه - (مسئولیت معنوی درجه اول )