عنوان

The Tetracyclines

شابک

3642703046

شابک

3642703062

شابک

9783642703041

شابک

9783642703065

شماره

b559535

عنوان اصلي

The Tetracyclines

نام عام مواد

[Book]

نام نخستين پديدآور

edited by J.J. Hlavka, J.H. Boothe.

محل نشرو پخش و غیره

Berlin, Heidelberg

نام ناشر، پخش کننده و غيره

Springer Berlin Heidelberg

تاریخ نشرو بخش و غیره

1985

عنوان فروست

Handbook of Experimental Pharmacology, Continuation of Handbuch der experimentellen Pharmakologie,, 78.

متن يادداشت

1 Historical Introduction --;References --;2 Fermentation and Mutational Development of the Tetracyclines --;A. Introduction --;B. The Producing Microorganisms --;C. The Fermentation Process --;D. Fermentation Technology --;E. Concluding Remarks --;References --;3 Structure Determination and Total Synthesis of the Tetracyclines --;A. Introduction --;B. Structure Determination --;C. Partial Synthesis from Derivatives --;D. Total Synthesis of Tetracycline Derivatives and Incomplete Syntheses --;E. Total Synthesis of 6-Demethyl-6-deoxytetracycline --;F. Total Synthesis of Fermentation Tetracyclines --;G. Total Synthesis of Tetracycline Analogues --;References --;4 Biosynthesis of the Tetracyclines --;A. Introduction --;B. Production Strains --;C. Building Units of Tetracyclines --;D. The Biosynthetic Pathway of Tetracyclines --;E. Regulation of the Biosynthesis of Tetracyclines --;E. Regulation of the Biosynthesis of Tetracyclines --;F. Biosynthesis of Macromolecules and the Production of Tetracyclines --;G. Conclusion --;References --;5 Chemical Modification of the Tetracyclines --;A. Introduction --;B. Semisynthetic Tetracyclines --;C. Totally Synthetic Unnatural Tetracyclines --;D. Overall Structure-Activity Relationships --;References --;6 Mode of Action of the Tetracyclines and the Nature of Bacterial Resistance to Them --;A. Introduction --;B. Mode of Action of the Tetracyclines: Studies Before 1964 --;C. Current Views on the Nature of Bacterial Protein Synthesis --;D. Effects of Tetracyclines on Protein Synthesis in Prokaryotes --;E. Binding of Tetracyclines to Macromolecules --;F. Molecular Basis of Tetracycline Action --;G. Relation Between Structure and Activity in the Tetracyclines --;H. Effects of Growth in the Presence of Low Tetracycline Concentrations on Microbial Metabolism --;I. Selective Toxicity of the Tetracyclines --;J. Transport of Tetracyclines into Bacteria --;K. Plasmid-Determined Resistance to the Tetracyclines --;L. Chromosomal Mutation to Tetracycline Resistance --;M. Conclusions --;References --;7 Clinical Uses of the Tetracyclines --;A. Antimicrobial Activity --;B. Clinical Uses --;C. Treatment of First Choice --;D. Effective Alternative Treatment --;E. Treatment of Clinical Syndromes --;F. Ineffective Treatment --;G. Dosage and Duration of Therapy --;References --;8 Nonmedical Uses of the Tetracyclines --;A. Historical --;B. Growth Promotion and Improved Feed Efficiency in Livestock --;C. Disease Prevention Effects of Chlortetracycline and Oxytetracycline --;D. Public Health Considerations --;E. Government Restrictions --;References.

متن يادداشت

The history of antibiotics may weIl have begun with the ancient Sudanese-Nubian civilization (see Chapter 1, "Historical Introduction"), but this volume reflects a more contemporary appraisal of the antibiotic era. Pearl River, NY J OSEPH J. 3 CHAPTER 2 Fermentation and Mutational Development of the Tetracyclines J.

موضوع مستند نشده

Medicine.

موضوع مستند نشده

Pharmacy.

موضوع مستند نشده

Toxicology.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

edited by J.J. Hlavka, J.H. Boothe.

مستند نام اشخاص تاييد نشده

J H Boothe

مستند نام اشخاص تاييد نشده

J J Hlavka

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y