عنوان

Current Progress in the Understanding of Secondary Brain Damage from Trauma and Ischemia :

شابک

3709163919

شابک

9783709163917

شماره

b536915

عنوان اصلي

Current Progress in the Understanding of Secondary Brain Damage from Trauma and Ischemia :

نام عام مواد

[Book]

ساير اطلاعات عنواني

Proceedings of the 6th International Symposium: Mechanisms of Secondary Brain Damage-Novel Developments, Mauls/Sterzing, Italy, February 1998

نام نخستين پديدآور

edited by Alexander Baethmann, Nikolaus Plesnila, Florian Ringel, Jörg Eriskat.

محل نشرو پخش و غیره

Vienna

نام ناشر، پخش کننده و غيره

Springer Vienna

تاریخ نشرو بخش و غیره

1999

نام خاص و کميت اثر

(viii, 120 pages)

عنوان فروست

Acta neurochirurgica., Supplement ;, 73.

متن يادداشت

Molecular and Cellular Mechanisms --;News from Cerebral Ischemia --;Remaining Problems in Severe Head Injury.

متن يادداشت

Information is provided from the basic and clinical sciences on the mechanisms damaging the brain from trauma or ischemia. New aspects involve the endoplasmic reticulum, mitochondrial failure, pathobiology of axonal injury, molecular signals activating glial elements, or the emerging therapeutical role of neurotrophins. Experimental issues involve a better analysis of the ischemic penumbra, the salvagable tissue. Therapeutic contributions reach from the environmental influence to gene expression, including neuroprotection, such as hibernation - mother nature's experiment - or hypothermia which is reported to induce cell swelling. Treatment issues deal also with thrombolysis and combination therapies, or with the clearance of adverse blood components - LDL/fibrinogen - by a novel procedure using heparin. Other highlights are discussing the specificities of pediatric vs. adult brain trauma, or the evolving role of the Apolipoprotein-E e4 gene in severe head injury. An update is also provided on an online assessment of the patient management during the pre- and early hospital phase in Southern Bavaria. The empirical observation of neuroworsening is analyzed in further details, whether this is a specificity autonomously driving the posttraumatic course. Finally, the unsolved question why drug trials in severe head injury have failed so far in view of the promising evidence from the laboratory is subjected to an expert analysis.

موضوع مستند نشده

Critical care medicine.

موضوع مستند نشده

Emergency medicine.

موضوع مستند نشده

Medicine.

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

edited by Alexander Baethmann, Nikolaus Plesnila, Florian Ringel, Jörg Eriskat.

مستند نام اشخاص تاييد نشده

Alexander Baethmann

مستند نام اشخاص تاييد نشده

Florian Ringel

مستند نام اشخاص تاييد نشده

Jörg Eriskat

مستند نام اشخاص تاييد نشده

Nikolaus Plesnila

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y