عنوان

Anticancer drug development /

شابک

0120726513 (alk. paper)

شماره

b535257

عنوان اصلي

Anticancer drug development /

نام عام مواد

[Book]

نام نخستين پديدآور

edited by Bruce C. Baguley, David J. Kerr

محل نشرو پخش و غیره

San Diego, Calif :

نام ناشر، پخش کننده و غيره

Academic Press,

تاریخ نشرو بخش و غیره

c2002

نام خاص و کميت اثر

xiii, 397 p. :

ساير جزييات

ill. (some col.) ;

ابعاد

29 cm

متن يادداشت

Includes bibliographical references and index

متن يادداشت

A brief history of cancer chemotherapy -- Novel targets in the cell cycle and cell cycle checkpoints -- Growth factor and signal transduction targets for cancer therapy -- Cell death pathways as targets for anticancer drugs -- Drug resistance pathways as targets -- Role of matrix metalloproteinases and plasminogen activators in cancer invasion and metastasis: therapeutic strategies -- Tumor vasculature as a target -- Gene-directed enzyme prodrug therapy -- Tumor antigens as targets for anticancer drug development -- Structure-based drug design and its contributions to cancer chemotherapy -- The contribution of synthetic organic chemistry to anticancer drug development -- Biosynthetic products for anticancer drug design and treatment: the bryostatins -- DNA-encoded peptide libraries and drug discovery -- Mechanism-based high-throughput screening for novel anticancer drug discovery -- Tumor cell cultures in drug development -- Screening using animal systems -- Relevance of preclinical pharmacology and toxicology to Phase I trial extrapolation techniques: relevance of animal toxicity -- Clinical trial design: incorporation of pharmacokinetic, pharmacodynamic, and pharmacogenetic principle -- Tumor imaging applications in the testing of new drugs -- Mechanistic approaches to Phase I clinical trials

بدون عنوان

0

موضوع مستند نشده

Antineoplastic agents

موضوع مستند نشده

Cancer-- Chemotherapy

موضوع مستند نشده

Drugs-- Design

موضوع مستند نشده

Antineoplastic Agents

موضوع مستند نشده

Drug Design

موضوع مستند نشده

Drug Evaluation, Preclinical

شماره

ويراست

شماره رده

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

Baguley, Bruce C

مستند نام اشخاص تاييد نشده

Kerr, David J

تاريخ عمليات

20020628142325.0

نام الکترونيکي

نوع ماده

[Book]

تكميل شده

Y