عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
شابک
شابک
1493922688
شابک
9781493922680
شابک اشتباه
9781493922697
شماره کتابشناسی ملی
شماره
dltt
عنوان و نام پديدآور
عنوان اصلي
Chemical biology
نام عام مواد
[Book]
ساير اطلاعات عنواني
methods and protocols /
نام نخستين پديدآور
edited by Jonathan E. Hempel, Charles H. Williams, Charles C. Hong.
وضعیت نشر و پخش و غیره
محل نشرو پخش و غیره
New York, NY :
نام ناشر، پخش کننده و غيره
Humana Press,
تاریخ نشرو بخش و غیره
c2015.
فروست
عنوان فروست
Methods in molecular biology,
عنوان فروست
Springer protocols
مشخصه جلد
1263
شاپا ي ISSN فروست
1064-3745 ;
یادداشتهای مربوط به کتابنامه ، واژه نامه و نمایه های داخل اثر
متن يادداشت
Includes bibliographical references and index.
یادداشتهای مربوط به مندرجات
متن يادداشت
Identification of Therapeutic Small Molecule Leads in Cultured Cells Using Multiplexed Pathway Reporter Read-outs -- Applying the Logic of Genetic Interaction to Discover Small Molecules That Functionally Interact with Human Disease Alleles -- Construction and Application of a Photo-cross-linked Chemical Array -- High Content Screening for Modulators of Cardiac Differentiation in Human Pluripotent Stem Cells -- Small Molecule High-Throughput Screening Utilizing Xenopus Egg Extract -- Fission Yeast-based High-throughput Screens for PKA Pathway Inhibitors and Activators -- A Method for High-throughput Analysis of Chronological Aging in Schizosaccharomyces pombe -- Protocols for the Routine Screening of Drug Sensitivity in the Human Parasite Trichomonas vaginalis -- Chemical Genetic Screens Using Arabidopsis thaliana Seedlings Grown on Solid Medium -- Small Molecule Screening Using Drosophila Models of Human Neurological Disorders -- High-throughput Small Molecule Screening in Caenorhabditis elegans -- Whole-organism Screening for Modulators of Fasting Metabolism Using Transgenic Zebrafish -- High Content Screening for Modulators of Cardiovascular or Global Developmental Pathways in Zebrafish -- Extraction Methods of Natural Products from Traditional Chinese Medicines -- Bioassay-guided Identification of Bioactive Molecules from Traditional Chinese Medicines -- NMR Screening in Fragment-Based Drug Design: A Practical Guide -- Practical Strategies for Small Molecule Probe Development in Chemical Biology -- Principal Component Analysis as a Tool for Library Design: A Case Study Investigating Natural Products, Brand-name Drugs, Natural Product-like Libraries, and Drug-like Libraries -- Small Molecule Library Screening by Docking with PyRx -- Fluorous Photoaffinity Labeling to Probe Protein-Small Molecule Interactions -- Identification of the Targets of Biologically Active Small Molecules Using Quantitative Proteomics -- Drug Affinity Responsive Target Stability (DARTS) for Small Molecule Target Identification -- Chemical Genomic Profiling via Barcode Sequencing to Predict Compound Mode of Action -- Image-Based Prediction of Drug Target in Yeast.
بدون عنوان
2
یادداشتهای مربوط به خلاصه یا چکیده
متن يادداشت
"This volume seeks to enable the discovery of tools in chemical biology by providing readers with various techniques ranging from initial chemical genetic screening to target identification. To successfully highlight the essential components of the chemical biology tool discovery process, the book is organizes into four parts that focus on platforms for molecular discovery in "in vitro "cellular systems, "in vivo" chemical genetic screening protocols, and methods used to discover functional protein targets. Written in the highly successful "Methods of Molecular Biology" series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Practical and informative, "Chemical Biology: Methods and Protocols" seeks to improve the success rate of the chemical biology field through the dissemination of detailed and experiential knowledge."--P. [4] of cover.
موضوع (اسم عام یاعبارت اسمی عام)
موضوع مستند نشده
Biochemical Phenomena
نام شخص - (مسئولیت معنوی برابر )
مستند نام اشخاص تاييد نشده
Hempel, Jonathan E.
مستند نام اشخاص تاييد نشده
Hong, Charles C.,1967-
مستند نام اشخاص تاييد نشده
Williams, Charles H., (Charles Houston)
مبدا اصلی
تاريخ عمليات
20190301104332.0
دسترسی و محل الکترونیکی
نام الکترونيکي
مطالعه متن کتاب اطلاعات رکورد کتابشناسی
نوع ماده
[Book]
اطلاعات دسترسی رکورد
تكميل شده
Y
