عنوان

siRNA design

شابک

9781627031189 )alk. paper(

عنوان اصلي

siRNA design

نام نخستين پديدآور

edited by Debra J. Taxman

محل نشرو پخش و غیره

New York

نام ناشر، پخش کننده و غيره

Humana Press,

تاریخ نشرو بخش و غیره

c2013

نام خاص و کميت اثر

xiii, 392 p. : ill. )some col.(.

عنوان فروست

Methods in molecular biology,1064-3745 ;942

عنوان فروست

Springer protocols,1949-2448

عنوان فروست

Series: Methods in molecular biology )Clifton, N.J.( ;v. 942.1064-3745

عنوان فروست

Series: Springer protocols.1949-2448

متن يادداشت

What parameters to consider and which software tools to use for target selection and molecular design of small interfering RNAs /Olga Matveeva --Methods for selecting effective siRNA target sequences using a variety of statistical and analytical techniques /Shigeru Takasaki --Designing functional siRNA with reduced off-target effects /Yuki Naito and Kumiko Ui-Tei --Design and screening of siRNAs against highly structured RNA targets /Neda Nasheri, John Paul Pezacki, and Selena M. Sagan --Engineering small interfering RNAs by strategic chemical modification /Jesper B. Bramsen and J▓rgen Kjems --Design, selection, and evaluation of highly specific and functional siRNA incorporating unlocked nucleobase analogs /Narendra Vaish and Pinky Agarwal --Design, preparation and evaluation of asymmetric small interfering RNA for specific gene silencing in mammalian cells /Chanil Chang ... ]et al.[ --Design of nuclease-resistant fork-like small interfering RNA )fsiRNA( /Elena L. Chernolovskaya and Marina A. Zenkova --Designing dual-targeting siRNA duplexes having two active strands that combine siRNA and MicroRNA-like targeting /Pal S╡trom --Strategies for designing and Validating immunostimulatory siRNAs /Michael P. Gantier --Designing efficient and specific endoribonuclease-prepared siRNAs /Vineeth Surendranath ... ]et al.[ --Short hairpin RNA-mediated gene silencing /Luke S. Lambeth and Craig A. Smith --Design of lentivirally expressed siRNAs /Ying Poi Liu and Ben Berkhout --Bifunctional short hairpin RNA )bi-shRNA( : design and pathway to clinical application /Donald D. Rao ... ]et al.[ --Design and chemical modification of synthetic short shRNAs as potent RNAi triggers /Anne Dallas and Brian H. Johnston --Production and application of long dsRNA in mammalian cells /Katerina Chalupnikova, Jana Nejepinska, and Petr Svoboda --Design of RNAi reagents for invertebrate model organisms and human disease vectors /Thomas Horn and Michael Boutros --Construction of shRNA expression plasmids for silkworm cell lines using single-stranded DNA and Bst DNA polymerase /Hiromitsu Tanaka --Designing effective amiRNA and multimeric amiRNA against plant viruses /Muhammad Fahim and Philip J. Larkin --Downregulation of plant genes with miRNA-induced gene silencing /Felipe Fenselau de Felippes.

متن يادداشت

Includes bibliographical references and index.

عنوان گونه گون

methods and protocols

عنصر شناسه ای

Small interfering RNA

عنصر شناسه ای

RNA, Small Interfering^agenetics--Laboratory Manuals

عنصر شناسه ای

Gene Silencing^aLaboratory Manuals

عنصر شناسه ای

Gene Targeting^amethods--Laboratory Manuals

عنصر شناسه ای

Laboratory Manuals

شماره

شماره رکورد غير از شماره رده بندي

شماره رده

شماره رکورد رده بندي

نشانه اثر

شماره رکورد غير از شماره رده بندي

عنصر شناسه اي

Taxman, Debra J

نوع ماده

English Book